"RND3" Related Products

Recombinant Human Rho Family GTPase 3, His-tagged

Cat. No. : RND3-2748H
Product Overview : Recombinant human RND3 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW =29.2kDa (261aa) confirmed by MALDI-TOF.
Description : Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS C
Purity : > 90% by SDS – PAGE.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 1mM EDTA, 0.1M NaCl.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : RND3 Rho family GTPase 3 [ Homo sapiens ]
Synonyms : RND3; Rho family GTPase 3; ARHE; Rho8; RhoE; memB; rho-related GTP-binding protein RhoE; protein MemB; OTTHUMP00000162685; OTTHUMP00000204380; OTTHUMP00000204381; small GTP binding protein Rho8; ras homolog gene family, member E; rho-related GTP-binding protein Rho8
Gene ID : 390
mRNA Refseq : NM_005168
Protein Refseq : NP_005159
MIM : 602924
UniProt ID : P61587
Chromosome Location : 2q23.3
Function : GTP binding; GTPase activity; nucleotide binding

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