"GGCT" Related Products

Recombinant Human GGCT, His-tagged

Cat. No. : GGCT-956H
Product Overview : Recombinant human GGCT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : GGCT, also known as gamma-glutamylcyclotransferase, belongs to the family of transferases, specifically the aminoacyltransferases. This protein catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. GGCT induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Molecular Weight : 23.2 kDa (208aa) confirmed by MALDI-TOF.
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII KKGETQTL.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Glutathione metabolism
Gene Name : GGCT gamma-glutamylcyclotransferase [ Homo sapiens ]
Synonyms : gamma-glutamylcyclotransferase;gam-ma-glutamyl cyclotransferase; GGC; GCTG; CRF21; C7orf24; MGC3077; FLJ11717; GGCT; OTTHUMP000002-02475; cytochrome c-releasing factor 21;Cytochrome c-releasing factor 21; EC 2.3.2.4
Gene ID : 79017
mRNA Refseq : NM_024051
Protein Refseq : NP_076956
MIM : 137170
UniProt ID : O75223
Chromosome Location : 7p15-p14
Function : acyltransferase activity; gamma-glutamylcyclotransferase activity; protein homodimerization activity; transferase activity

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