"TREX2" Related Products

Recombinant Human TREX2, His-tagged

Cat. No.: TREX2-965H
Product Overview: Recombinant human TREX2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: TREX2 is an enzyme containing 3-prime-to-5-prime exonuclease activity and removes mismatched, modified, fragmented, and normal nucleotides to generate the appropriate 3-prime termini for subsequent steps in the DNA metabolic pathways. This enzyme is involved in DNA replication, repair, and recombination.
Source: E.coli.
Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol.
Molecular Weight: 28.0 kDa (256aa) confirmed by MALDI-TOF.
Purity: > 95% by SDS - PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAV HRSSL ENPEHDESGA LVLPRVLDKL TLCMCPERPF TAKASEITGL SSEGLARCRK AG FDGAVVRT LQAFLSRQAG PICLVAHNGF DYDFPLLCAE LRRLGARLPR DTV CLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF RAEPSAAHSA EGD VH TLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: TREX2 three prime repair exonuclease 2 [ Homo sapiens ]
Synonyms: three prime repair exonuclease 2; TREX2;three prime repair exonuclease 2; OTTHUMP00000025920; OTTHUM- P00000025922; 3"-5" exonuclease TRE- X2 long form; EC 3.1.11.2; 3"-5" exonu clease TREX2
Gene ID: 11219
mRNA Refseq: NM_080701
Protein Refseq: NP_542432
MIM: 300370
UniProt ID: Q9BQ50
Chromosome Location: Xq28
Function: 3"-5"-exodeoxyribonuclease activity; exodeoxyribonuclease III activity; exonuclease activity; hydrolase activity; nucleic acid binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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