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Recombinant Human Ras Homolog Gene Family, Member C, His-tagged

Cat.No. : RHOC-2768H
Product Overview : Recombinant human RhoC protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.8 kDa (210aa).
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Cat. No. : RHOC-2768H
Description : RhoC, also known as rho-related GTP-binding protein RhoC, is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It cycles between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. RhoC promotes reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
Purity : > 90% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVY VPTVFE NYIADIEVDG KQVELALWDT AGQEDYDRLRPLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRQDEHTRRE LAKMKQEPVR SEEG RDMANR ISAFGYLECSAKTKEGVREV FEMATRAGLQ VRKNKRRRGC.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Axon guidance; Signaling by GPCR; Signaling by Rho GTPases
Gene Name : RHOC ras homolog gene family, member C [ Homo sapiens ]
Synonyms : ras homolog gene family, member C; H9; ARH9; ARHC; RHOH9; MGC1448; MGC61427; RHOC; rho-related GTP-binding protein RhoC; rhoC GTPase; oncogene RHO H9; rho cDNA clone 9; RAS-related homolog 9; OTTHUMP00000013803; OTTHUMP00000013804; OTTHUMP00000013806; small GTP binding protein RhoC;RhoC; Rho-related GTP-binding protein RhoC; Rho cDNA clone 9; h9
Gene ID : 389
mRNA Refseq : NM_001042678
Protein Refseq : NP_001036143
MIM : 165380
UniProt ID : P08134
Chromosome Location : 1p13.1
Function : GTP binding; GTPase activity; nucleotide binding; protein binding; signal transducer activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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