"SRI" Related Products

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Recombinant Human SRI, His-tagged

Cat. No. : SRI-3478H
Product Overview : Recombinant human SRI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT, 0.1mM PMSF
Molecular Weight : 24.1 kDa (221aa) confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGSMAYPGHP GAGGGYYPGG YGGAPGGPAF PGQTQDPLYG YFAAVAGQDG QIDADELQRC LTQSGIAGGY KPFNLETCRL MVSMLDRDMS GTMGFNEFKE LWAVLNGWRQ HFISFDTDRS GTVDPQELQK ALTTMGFRLS PQAVNSIAKR YSTNGKITFD DYIACCVKLR ALTDSFRRRD TAQQGVVNFP YDDFIQCVMS V
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : SRI sorcin [ Homo sapiens ]
Synonyms : CP22; SRI; V19; CP-22; H_RG167B05.1; 22 kDa protein;calcium binding protein amplified in mutlidrug-resistant cells; OTTHUMP00000205590; Sorcin; SCN; FLJ26259;OTTHUMP00000206386; OTTHUMP00000213080
Gene ID : 6717
mRNA Refseq : NM_003130
Protein Refseq : NP_003121
MIM : 182520
UniProt ID : P30626
Chromosome Location : 7q21.1
Function : calcium channel regulator activity; calcium ion binding; receptor binding

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