"RALA" Related Products

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Recombinant Human V-Ral Simian Leukemia Viral Oncogene Homolog A (ras related), His-tagged

Cat. No.: RALA-1777H
Product Overview: Recombinant humanRALA protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.
Description: RALA (Ras-relatedprotein Ral-A) belongs to the small GTPase superfamily, Ras family ofproteins. RALA mediates a distinct downstream signaling pathway from Ras thatfacilitates cellular transformation. RALA is also thought to be involved innumerous signaling cascades, including regulation of the cytoskeleton, vesicletrafficking, and endocytosis.
Concentration: 0.5 mg/ml
Source: Human
Host: E.coli
Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 2mMDTT, 100mM NaCl, and 0.1mM PMSF.
Purity: > 90% by SDS -PAGE
Sequence: 1-203 amino acids:MGSSHHHHHH SSGLVPRGSH MGSHMAANKP KGQNSLALHK VIMVGSGGVG KSALTLQFMY DEFVEDYEPTKADSYRKKVV LDGEEVQIDI LDTAGQEDYA AIRDNYFRSG EGFLCVFSIT EMESFAATAD FREQILRVKEDENVPFLLVG NKSDLEDKRQ VSVEEAKNRA EQWNVNYVET SAKTRANVDK VFFDLMREIR ARKMEDSKEKNGK
Molecular Mass: 31.8 kDa(291aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: RALA
Gene Name: RALA v-ral simian leukemia viraloncogene homolog A (ras related) [ Homo sapiens ]
Synonyms: RALA; v-ral simian leukemia viral oncogene homolog A (rasrelated); RAL; MGC48949; ras-related protein Ral-A; OTTHUMP00000158977;OTTHUMP00000207663; RAS-like protein A; Ras family small GTP binding proteinRALA
Gene ID: 5895
mRNA Refseq: NM_005402
Protein Refseq: NP_005393
MIM: 179550
UniProt ID: P11233
Chromosome Location: 7p15-p13
Pathway: Arf6trafficking events; ErbB1 downstream signaling; NGF signalling via TRKA fromthe plasma membrane; Pancreatic cancer; Pathways in cancer; Signalling byNGF; Signalling to ERKs; Signalling to RAS; p38MAPK events
Function: Edg-2lysophosphatidic acid receptor binding; GTP binding; GTPase activity;nucleotide binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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