"PTN" Related Products

Expand
Expand

Recombinant Human Pleiotrophin

Cat. No.: PTN-630H
Product Overview: Recombinant humanPTN protein, was expressed in E. coli and purified by using conventionalchromatography techniques.
Description: PTN and Midkine arestructurally related heparin-binding neurotrophic factors, whose expressionis developmentally regulated. The expression pattern of these neurotrophicfactors suggests function in neurogenesis, cell migration, secondaryorganogenetic induction, and mesoderm epithelial interaction. The expressionof PTN increases during the process of brain embryogenesis and reachesmaximum levels at time of birth. The physiological roles of PTN and Midkineare largely unknown, but these neurotrophins have been implicated in thepathogenesis of neuroblastomas.
Source: Human
Host: E. coli
Form: Lyophilized from 5 mMNa3PO4, pH 7.4. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Purity: > 98% pure bySDS-PAGE and HPLC
Sequence: Region ofPleiotrophin protein corresponding to amino acids GKKEKPEKKV KKSDCGEWQWSVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSLKRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD.
Molecular Mass: 15.4 kDa
Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions.
Storage: Store at 4 deg Cuntil reconstitution. Following reconstitution aliquot and freeze at -20 degC for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol: PTN
Gene Name: PTN pleiotrophin [ Homosapiens ]
Synonyms: PTN; pleiotrophin;HARP; HBNF; HBGF8; NEGF1; Heparin-binding growth-associated molecule; HB-GAM;Heparin-binding growth factor 8; Osteoblast-specific factor 1; OSF-1;Heparin-binding neurite outgrowth-promoting factor 1; HBNF-1; Heparin-bindingbrain mitogen; HBBM; HBGF-8; HBNF1; heparin affin regulatory protein; heparinbinding growth factor 8; neurite growth-promoting factor 1
Gene ID: 5764
mRNA Refseq: NM_002825
Protein Refseq: NP_002816
MIM: 162095
UniProt ID: P21246
Chromosome Location: 7q33
Pathway: Syndecan-3-mediatedsignaling events
Function: growth factoractivity; heparin binding; protein phosphatase inhibitor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.