Recombinant Mouse Iterleukin 3

• Cat.No.: ll3-542M
• Product Overview: Recombinant humanll3 was expressed in E. coli and prified recombinant Mouse ll3 protein.

Specification

• Cat. No.: ll3-542M
• Description: ll3 is ahematopoietic growth factor that promotes the survival, differentiation andproliferation of committed progenitor cells of the megakaryocyte,granulocyte-macrophage, erythroid, eosinophil, basophil and mast celllineages. Produced by T cells, mast cells and eosinophils, ll3 enhancesthrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity.Its ability to activate monocytes suggests that ll3 may have additionalimmunoregulatory roles. Many of the ll3 activities depend upon co-stimulationwith other cytokines. ll3 is species-specific, variably glycosylatedcytokine.
• Source: Mouse
• Host: E. coli
• Form: Suppliedlyophilized with no additives. Reconstitute in water to a concentration of0.1-1.0 mg/ml. Keep pH below 5.0.
• Purity: >98% pure by SDSPAGE and HPLC
• Sequence: Region of IL3protein corresponding to amino acids MDTHRLTRTL NCSSIVKEII GKLPEPELKTDDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKLRFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC.
• Molecular Mass: 15.1 kDa
• Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions.
• Storage: Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: Il3

Gene Information

• Gene Name: Il3 interleukin 3 [ Musmusculus ]
• Synonyms: Il3; interleukin 3; BPA; PSF; HCGF; Il-3; MCGF; Csfmu; nterleukin-3;TTMUSP00000005831; ast cell growth factor; P-cell-stimulating factor; hematopoieticgrowth factor; multipotential colony-stimulating factor
• Gene ID: 16187
• mRNA Refseq: NM_010556
• Protein Refseq: NP_034686
• UniProt ID: P01586
• Chromosome Location: 11
• Pathway: Apoptosis; Asthma; Cytokine-cytokinereceptor interaction; Fc epsilon RI signaling pathway; Hematopoietic celllineage; IL-3 Signaling Pathway; Jak-STAT signaling pathway; Senescence andAutophagy
• Function: cytokineactivity; growth factor activity; interleukin-3 receptor binding