Recombinant Human Tumor Necrosis Factor (ligand) Superfamily, Member 14
| Cat.No. : | TNFSF14-354H |
| Product Overview : | Recombinant human TNFSF14was expressed in E. coli and purified recombinant Human TNFSF14 protein. |
- Specification
- Gene Information
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| Cat. No. : | TNFSF14-354H |
| Description : | TNFSF14 belongs tothe TNF family of ligands, and can signal through the herpes virus entrymediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoyreceptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8tumor infiltrating lymphocytes, granulocytes, and monocytes. TNFSF14 has theability to active NF kb, to co-stimulate the activation of lymphocytes and toinduce apoptosis in certain human tumor cells. |
| Source : | Human |
| Host : | E. coli |
| Form : | Supplied as alyophilized powder. |
| Purity : | > 98% pure by SDSPAGE and HPLC |
| Sequence : | 1-248 amino acids:MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSNEEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDKKRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSEDSYKD |
| Molecular Mass : | 20.1 kDa |
| Applications : | Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions. |
| Storage : | Store at 4 deg Cuntil reconstitution. Following reconstitution aliquot and freeze at -20 degC for long term storage. Avoid repeated freeze/thaw cycles. |
| OfficialSymbol : | TNFSF14 |
| Gene Name : | TNFSF14tumor necrosis factor (ligand) superfamily, member 14 [ Homo sapiens ] |
| Synonyms : | TNFSF14; tumor necrosis factor(ligand) superfamily, member 14; LTg; TR2; CD258; HVEML; LIGHT; deltatransmembrane LIGHT; herpesvirus entry mediator A; ligand for herpesvirusentry mediator; tumor necrosis factor receptor-like 2; tumor necrosis factorsuperfamily member LIGHT; CD258 antigen; Herpesvirus entry mediator-ligand;ligand for herpesvirus entry mediator; tumor necrosis factor ligandsuperfamily, member 14; HVEM-L; Tumor necrosis factor ligand superfamilymember 14, membrane form; Tumor necrosis factor ligand superfamily member 14,soluble form |
| Gene ID : | 8740 |
| mRNA Refseq : | NM_003807 |
| Protein Refseq : | NP_003798 |
| MIM : | 604520 |
| UniProt ID : | O43557 |
| Chromosome Location : | 19p13.3 |
| Pathway : | Cytokine-cytokine receptorinteraction; Herpessimplex infection |
| Function : | caspase inhibitor activity;cytokine activity; tumor necrosis factor receptor binding |
Products Types
| ◆ Lysates | ||
| TNFSF14-891HCL | Recombinant Human TNFSF14 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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