Native Human Chorionic Gonadotropin, Beta Polypeptide


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Native Human Chorionic Gonadotropin, Beta Polypeptide

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Cat. No. : CGB-359H
Product Overview : Native human CGB was expressedin Human Pregnancy Urine. Native Human Chorionic Gonadotropin beta.
Description : CGB is a glycoprotein hormoneproduced during pregnancy that is made by the developing embryo afterconception and later by the syncytiotrophoblast (part of the placenta). Sometumors make this hormone, measured elevated levels when the patient is notpregnant can lead to a cancer diagnosis. However, it is not known whetherthis production is a contributing cause or an effect of tumorigenesis. Thepituitary analog of CGB, known as luteinizing hormone (LH), is produced inthe pituitary gland of males and females of all ages.
Form : Lyophilized in 50 mMammonium bicarbonate.
Source : Human PregnancyUrine
Purity : > 98% by SDS-PAGEanalysis; Purified by HPLC.
Reconstitution : Centrifuge vialprior to opening. Reconstitute with NaPO4, pH 7.5 at 1.0-2.0 mg/ml.
Certification : Raw materials testednegative against HIV Antigen, HbsAg, HBeAg, Hepatitis Cantibody andHepatitis A antibody by FDA approved methods.
Contaminants : hCG 0.973%; LH<0.0001%; FSH <0.0001%; TSH <0.0001%
Storage : Store at -20°C.
Pathways : Glycoproteinhormones; Metabolism; Metabolism of amino acids and derivatives; Peptidehormone biosynthesis
PDBrendering based on 1hcn. :

Gene Name : CGB chorionic gonadotropin, betapolypeptide [ Homo sapiens ]
Official Symbol : CGB
Synonyms : CGB; chorionic gonadotropin, beta polypeptide; CGB3; CGB5; CGB7;CGB8; hCGB; choriogonadotropinsubunit beta; CG-beta; chorionic gonadotropin beta chain; chorionicgonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionicgonadotropin beta 3 subunit; Choriogonadotropin subunit beta
Gene ID : 1082
mRNA Refseq : NM_000737
Protein Refseq : NP_000728
MIM : 118860
UniProt ID : P01233
Chromosome Location : 19q13.3
Function : hormoneactivity

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