"CSF2" Related Products

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Recombinant Rhesus Macaque Colony Stimulating Factor 2 (granulocyte-macrophage)

Cat. No.: CSF2-360R
Product Overview: RecombinantRhesus Macaque CSF2 is a single non-glycosylated polypeptide chain containing127 amino acids.
Description: CSF2 wasinitially characterized as a growth factor that can support the in vitrocolony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types in response to cytokine or immune andinflammatory stimuli. On mature hematopoietic cells, CSF2 is a survivalfactor for and activates the effectors functions of granulocytes monocytes,macrophages, and eosinophils.
Source: Rhesus Macaque
Host: E. coli
Form: Lyophilized from a 0.2 um sterile filteredsolution of PBS, pH 7.4.
Purity: >98%by SDS-PAGE and HPLC analyses.
Sequence: APARSPSPGTQPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMMASHYKQHCPP TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE
Molecular Weight: 14.4 kDa
Biological Activity: Fully biologicallyactive when compared to standard. The ED50 as calculated by thedose dependant stimulation of the proliferation of human TF-1 cells is lessthan 0.1 ng/ml, corresponding to a Specific Activity of 1.0×107IU/mg.
Endotoxin: < 0.1 ng/μg ofprotein.
Reconstitution: Centrifugevial prior to opening. Reconstitute in sterile distilled water or aqueousbuffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stocksolutions should be apportioned into working aliquots and stored at<-20°C. Further dilutions should be made in appropriate bufferedsolutions.
Storage: Thelyophilized protein is stable at 2-4°C, but should be kept desiccated at-20°C for long term storage. After reconstitution, the protein is stable for1 week at 2-4°C. For long term storage, aliquot and freeze at -80°C. Avoidrepeated freeze-thaw cycles.
OfficialSymbol: CSF2
Pathways: Cytokine-cytokinereceptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway;Amoebiasis;HTLV-1 infection; Natural killer cell mediated cytotoxicity; Rheumatoidarthritis; Salmonella infection; T cell receptor signaling pathway
Gene Name: CSF2 colony stimulating factor2 (granulocyte-macrophage) [ Macaca mulatta ]
Synonyms: CSF2; colonystimulating factor 2 (granulocyte-macrophage); GM-CSF; Granulocyte-macrophage colony-stimulating factor; Uncharacterized protein; Mmu.3665
Gene ID: 574371
mRNA Refseq: NM_001032949
Protein Refseq: NP_001028121
UniProt ID: Q9GL44
Chromosome Location: 6

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