"CST3" Related Products

Recombinant Human Cystatin C

Cat. No.: CST3-376H
Product Overview: Recombinant human CST3was expressed in E.coli.
Description: CST3 is a member ofthe type 2 cystatin superfamily. It is a potent inhibitor of cysteineproteinases, both endogenous (lysosomal cathepsins), and pathogenic. CST3 isa 13kDa secreted protein which is found in high concentrations in biologicalfluids and is thought to be expressed by all human nucleated cells. Changesin CST3 have been documented in a number of cardiovascular diseases,including atherosclerosis, amyloid angiopathy and myocardial infarction. Itslow molecular weight also means that CST3 can be used as a marker of renalfailure.
Form: Purified recombinantprotein–lyophilized.
Application: Functional Assays
Preparation: Purified recombinantCST3 expressed in E.coli.
Buffer Solution: TRIS buffered saline
Reconstitution: Reconstitute withdeionized water. Care should be taken during reconstitution as the proteinmay appear as a film at the bottom of the vial. AbD Serotec recommend thatthe vial is gently mixed after reconstitution.
Purity: >95% by SDS PAGE
Storage: Prior toreconstitution store at +4oC. After reconstitution store at -70oC.Storage in frost-free freezers is not recommended. This product should bestored undiluted. Avoid repeated freezing and thawing as this may denaturethe antibody. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Pathways: Amyloids; Salivarysecretion
Gene Name: CST3 cystatin C [ Homosapiens ]
Official Symbol: CST3
Synonyms: CST3;cystatin C; ARMD11;MGC117328; cystatin-C; cystatin 3; cystatin-3; gamma-trace;OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182;post-gamma-globulin; bA218C14.4 (cystatin C); neuroendocrine basicpolypeptide
Gene ID: 1471
mRNA Refseq: NM_000099
Protein Refseq: NP_000090
MIM: 604312
UniProt ID: P01034
Chromosome Location: 20p11.2
Function: beta-amyloidbinding; cysteine-type endopeptidase inhibitor activity; peptidase inhibitoractivity; protease binding

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