Recombinant Human Thyrotropin-Releasing Hormone

• Cat.No.: TRH-703H
• Product Overview: Recombinant human TRHis Synthetic, which having a molecule weight of 362.39 Da.

Specification

• Cat. No.: TRH-703H
• Description: Protirelinstimulates the secretion of pituitary thyroid stimulating hormone from theanterior pituitary and has been shown that protirelin increases secretion ofprolactin. Protirelin is identified as 5-oxo-L-prolyl-L-histidyl-L-prolineamide. It is a synthetic tripeptide that is believed to be structurallyidentical to the naturally-occurring thyrotropin-releasing hormone producedby the hypothalamus Human TRH C16H22N6O4 has a MW of 362.39 Da.
• Source: Synthetic
• Species: Human
• MolecularWeight: 362.39 Da
• Form: Human Thyrotropinreleasing hormone was lyophilized with no additives.
• Appearance: Sterile FilteredWhite lyophilized (freeze-dried) powder.
• Purity: Greater than 98.0%as determined by: Analysis by RP-HPLC, anion-exchange FPLC, and analysis byreducing and non-reducing SDS-PAGE Silver Stained.
• Endotoxin Level: Less than 0.1 ng/µg(1 EU/µg) of Recombinant Human Thyrotropin releasing hormone.
• Storage: Lyophilized TRHalthough stable at room temperature for 3 weeks, should be stored desiccatedbelow -18°C. Upon reconstitution TRH should be stored at 4°C between 2-7 daysand for future use below -18°C. For long term storage it is recommended toadd a carrier protein (0.1% HSA or BSA). Avoid freeze-thaw cycles.
• OfficialSymbol: TRH

Gene Information

• Gene Name: TRH thyrotropin-releasing hormone[ Homo sapiens ]
• Synonyms: TRH;thyrotropin-releasing hormone; prothyroliberin; MGC125964; MGC125965;OTTHUMP00000216039; OTTHUMP00000216040
• Gene ID: 7200
• mRNA Refseq: NM_007117
• Protein Refseq: NP_009048
• MIM: 613879
• UniProt ID: P20396
• Chromosome Location: 3q13.3-q21
• Pathway: Class A/1(Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstreamsignaling; GPCR ligand binding; Peptide ligand-binding receptors; SignalTransduction; Signaling by GPCR
• Function: neuropeptide hormoneactivity; thyrotropin-releasing hormone activity