Recombinant Human Creatine Kinase, Muscle

• Cat.No.: CKM-5380H
• Product Overview: Recombinant humanCKM Isoenzyme with identical amino acid sequence as the native enzyme (humangene). Itsmolecular weight is 88000 Dalton.

Specification

• Cat. No.: CKM-5380H
• Description: Creatine kinase(CKM), also known as creatine phosphokinase (CPK) or phospho-creatine kinase(and sometimes incorrectly as creatinine kinase), is an enzyme expressed byvarious tissues and cell types. CKM catalyses the conversion of creatine andconsumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) andadenosine diphosphate (ADP). This CK enzyme reaction is reversible, such thatalso ATP can be generated from PCr and ADP.
• Source: Human cardiactissues
• Species: Human
• Form: Liquid in 20 mMTris-HCl, pH 6.8 + 1 mM DTT + 1 mM EDTA.
• Molecular Weight: 88.0 kDa
• Purity: > 99% asdetermined by SDS-PAGE analyses
• Specific Activity: 892 IU/mg
• Contaminants: None detected bySDS-PAGE.
• Biohazard: Not hazardous. Usenormal laboratory precautions and procedures when handling.
• Storage: Store in workingaliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: CKM

Gene Information

• Gene Name: CKM creatine kinase, muscle [ Homosapiens ]
• Synonyms: CKM; creatinekinase, muscle; CKMM; M-CK; creatine kinase M-type; creatine kinase-M;creatine kinase M chain; EC 2.7.3.2
• Gene ID: 1158
• mRNA Refseq: NM_001824
• Protein Refseq: NP_001815
• MIM: 123310
• UniProt ID: P06732
• Chromosome Location: 19q13.2-q13.3
• Pathway: Arginine and prolinemetabolism; Creatine metabolism; Creatine pathway; Metabolic pathways;Metabolism; Metabolism of amino acids and derivatives; Regulation ofretinoblastoma protein; Urea cycle and metabolism of amino groups;creatine-phosphate biosynthesis
• Function: ATP binding;creatine kinase activity; nucleotide binding