"CXCL16" Related Products

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Recombinant Human Chemokine (C-X-C motif) Ligand 16

Cat. No.: CXCL16-372H
Product Overview: Recombinant human CXCL16gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmicdomain and transmembrane sequence containing approximately 20 amino acids.
Description: Chemokine (C-X-Cmotif) Ligand 16 (CXCL16) is a member of the CXC chemokine amily and signalsthrough the CXCR6 receptor. CXCL16 may play a role in attracting lmphocytesubsets during inflammation and may facilitate certain immune responses. Thechemokine domain of CXCL16 contains six cysteine residues including the four highlyconserved cysteine residues characteristic of CXC chemokines. Theextracellular portion of CXCL16 contains a chemokine domain and an extendedC-terminal "mucin-like stalk" sequence. The extracellular domaincontains 89 amino acid residues (86 aa residues for the mouse homolog).
Source: E. coli
Species: Human
Form: Lyophilized withoutadditives.
Molecular Weight: 10.1 kDa
Purity: >98% by SDS-PAGE.
Endotoxin Level: <0.1 ng/µgCXCL16.
Biological Activity: Determined by itsability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/mL.
Reconstitution: Centrifuge vialprior to opening. Add sterile distilled water to a concentration of 0.1-1.0mg/mL. Do not vortex. After complete solubilization of the protein, it can befurther diluted to other aqueous solutions.
Storage: Store at -20°C.After reconstitution, store in working aliquots at -20°C. Avoid freeze-thawcycles.
OfficialSymbol: CXCL16
Gene Name: CXCL16 chemokine (C-X-C motif)ligand 16 [ Homo sapiens ]
Synonyms: CXCL16; chemokine(C-X-C motif) ligand 16; SRPSOX; CXCLG16; SR-PSOX; SCYB16; C-X-C motifchemokine 16; OTTHUMP00000115953; CXC chemokine ligand 16; small-induciblecytokine B16; transmembrane; Small-inducible cytokine B16; chemokine CXCL16;scavenger receptor for phosphatidylserine and oxidized low densitylipoprotein
Gene ID: 58191
mRNA Refseq: NM_001100812
Protein Refseq: NP_001094282
MIM: 605398
UniProt ID: Q9H2A7
Chromosome Location: 17p13
Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; G alpha (i) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Signal Transduction; Signaling by GPCR
Function: chemokine activity;low-density lipoprotein receptor activity; receptor binding; scavengerreceptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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