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Recombinant Human Ribonucleotide Reductase M2, T7-tagged

Cat.No. : RRM2-820H
Product Overview : Recombinant RRM2 protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 44878Da (389aa).
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Cat. No. : RRM2-820H
Description : Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is anenzymethat in humans is encoded by the RRM2gene.
Sequences of amino acids : MLSLRVPLP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYEISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRG LMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEELTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT
Clonality : N/A
Purity : 95% by SDS - PAGE
Applications : MS. SDS
Gene Name : RRM2 ribonucleotide reductase M2 [Homo sapiens]
Synonyms : RRM2; RR2M; RR2; R2; EC 1.17.4.1; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; OTTHUMP00000115511; OTTHUMP00000214026
Gene ID : 6241
mRNA Refseq : NM_001034
Protein Refseq : NP_001025
MIM : 180390
UniProt ID : P31350
Chromosome Location : 2P25-P24
Pathway : Glutathione metabolism; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; p53 signaling pathway
Function : Oxidoreductase activity; protein binding; ribonucleoside-diphosphate reductase activity; ribonucleoside-diposphate reductase activity; transition metal ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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