Recombinant Human Histone Deacetylase 1, His-FLAG Tagged
Cat.No. : | HDAC1-374H |
Product Overview : | Recombinant Humanfull-length HDAC1 with C-terminal His-FLAG Tagged. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC1-374H |
Description : | HDAC1belongs to the Histone Deacetylase/acuc/apha family and is a component of theHistone Deacetylase complex. HDAC1 interacts with Retinoblastomatumor-suppressor protein (Rb) and this complex is a key element in thecontrol of cell proliferation and differentiation. Together withMetastasis-Associated Protein-2, it deacetylates p53 and modulates its effecton cell growth and apoptosis. |
Source : | Baculovirus-infectedSf9 Insect cells |
Species : | Human |
Form : | Liquid in 25 mMTris-HCl, pH 8.0 + 130 mM NaCl + 0.05% Tween-20 + 10% Glycerol. |
Molecular Weight : | 56 kDa |
Applications : | Enzyme kinetics; Screeninginhibitors; Selectivity profiling.The optimal concentration should bedetermined by the user for each specific application. |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | HDAC1 |
Gene Name : | HDAC1 histone deacetylase 1 [ Homosapiens ] |
Synonyms : | HDAC1; histone deacetylase 1; DKFZp686H12203;GON-10; HD1; RPD3; RPD3L1; OTTHUMP00000008745; reduced potassium dependency,yeast homolog-like 1; DKFZp686H12203; EC 3.5.1.98 |
Gene ID : | 3065 |
mRNA Refseq : | NM_004964 |
Protein Refseq : | NP_004955 |
MIM : | 601241 |
UniProt ID : | Q13547 |
Chromosome Location : | 1p34 |
Pathway : | Androgen Receptor Signaling Pathway; CellCycle; Chronic myeloid leukemia; Delta-Notch Signaling Pathway; E2Ftranscription factor network; EGFR1 Signaling Pathway; Energy Metabolism; G0and Early G1; Glucocorticoid receptor regulatory network; Hedgehog signalingevents mediated by Gli proteins; Hemostasis; Huntington"s disease; IL-6Signaling Pathway; Mitotic G1-G1/S phases; Notch signaling pathway |
Function : | enzyme binding; histonedeacetylase activity; hydrolase activity; identical protein binding;transcription activator activity; transcription factor activity;transcription factor binding; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
HDAC1-549H | Recombinant Human HDAC1 Protein (1-482 aa), His-SUMO-tagged | +Inquiry |
HDAC1-2469R | Recombinant Rat HDAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC1-060H | Recombinant Human HDAC1 Protein, His/FLAG-tagged | +Inquiry |
Hdac1-3366M | Recombinant Mouse Hdac1 Protein, Myc/DDK-tagged | +Inquiry |
HDAC1-45H | Recombinant Human HDAC1 Protein, His/FLAG-tagged | +Inquiry |
◆ Lysates | ||
HDAC1-5608HCL | Recombinant Human HDAC1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2283 | HDAC1 Immunoprecipitation (IP) & Activity Assay Kit | +Inquiry |
Kit-1737 | HDAC1 Kinetic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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