Recombinant Human Insulin-Like Growth Factor 2 Receptor IGF2R-619H

Recombinant Human Insulin-Like Growth Factor 2 Receptor

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Recombinant Human Insulin-Like Growth Factor 2 Receptor

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Cat. No. : IGF2R-619H
Product Overview : Recombinant Human IGF2R is expressed in E.coli.
Description : IGF2R is a protein that inhumans is encoded by the IGF2R gene. IGF2R is a multifunctional proteinreceptor that binds insulin-like growth factor 2 (IGF2) at the cell surfaceand mannose-6-phosphate (M6P)-tagged proteins in the trans-Golgi network.
Source : Produced recombinantlyin E. coli.
Species : Human
Molecular Weight : 7.496 kDa-confirmedby Mass Spectrometry
Purity : Greaterthan 95 % (by HPLC and N-terminal sequence analysis)
Endotoxin Level : Less than 0.1 EU/μg
Biological Activity : Type 2 IGF receptorbinding assay: ED50 < 100 ng/ml; IGF binding protein assay: ED50> 1000 ng/ml; Stimulation of protein synthesis in rat L6 myoblasts:ED50 < 100 ng/ml
Stateand appearance : Dried from 0.1 Macetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa).
N-terminal sequenceanalysis : 7 residues Greater than 95 % single sequence
Storage : At least 2 years at 2-4°C (lyophilized).
OfficialSymbol : IGF2R
Gene Name : IGF2Rinsulin-like growth factor 2 receptor [ Homo sapiens ]
Synonyms : IGF2R; insulin-likegrowth factor 2 receptor; MPR1; MPRI; CD222; CIMPR; M6P-R; cation-independentmannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptorOTTHUMP00000017536; CI Man-6-p Receptor; CI-MPR; M6PR; 300 kDa mannose6-phosphate receptor; MPR 300; insulin-like growth factor II receptor; IGF-IIreceptor; M6P/IGF2 receptor; M6P/IGF2R; CD222 antigen
Gene ID : 3482
mRNA Refseq : NM_000876
Protein Refseq : NP_000867
MIM : 147280
UniProt ID : P11717
Chromosome Location : 6q25-q27
Pathway : Clathrin derivedvesicle budding; Golgi Associated Vesicle Biogenesis; Lysosome; MembraneTrafficking; trans-Golgi Network Vesicle Budding
Function : glycoproteinbinding; insulin-like growth factor binding; insulin-like growth factor-activatedreceptor activity; mannose binding; phosphoprotein binding; protein binding; receptoractivity; transporter activity

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