Recombinant Human Insulin-Like Growth Factor 2 Receptor


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Recombinant Human Insulin-Like Growth Factor 2 Receptor

IGF2R Related Products

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Cat. No. : IGF2R-619H
Product Overview : Recombinant Human IGF2R is expressed in E.coli.
Description : IGF2R is a protein that inhumans is encoded by the IGF2R gene. IGF2R is a multifunctional proteinreceptor that binds insulin-like growth factor 2 (IGF2) at the cell surfaceand mannose-6-phosphate (M6P)-tagged proteins in the trans-Golgi network.
Source : Produced recombinantlyin E. coli.
Species : Human
Molecular Weight : 7.496 kDa-confirmedby Mass Spectrometry
Purity : Greaterthan 95 % (by HPLC and N-terminal sequence analysis)
Endotoxin Level : Less than 0.1 EU/μg
Biological Activity : Type 2 IGF receptorbinding assay: ED50 < 100 ng/ml; IGF binding protein assay: ED50> 1000 ng/ml; Stimulation of protein synthesis in rat L6 myoblasts:ED50 < 100 ng/ml
Stateand appearance : Dried from 0.1 Macetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa).
N-terminal sequenceanalysis : 7 residues Greater than 95 % single sequence
Storage : At least 2 years at 2-4°C (lyophilized).
OfficialSymbol : IGF2R
Gene Name : IGF2Rinsulin-like growth factor 2 receptor [ Homo sapiens ]
Synonyms : IGF2R; insulin-likegrowth factor 2 receptor; MPR1; MPRI; CD222; CIMPR; M6P-R; cation-independentmannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptorOTTHUMP00000017536; CI Man-6-p Receptor; CI-MPR; M6PR; 300 kDa mannose6-phosphate receptor; MPR 300; insulin-like growth factor II receptor; IGF-IIreceptor; M6P/IGF2 receptor; M6P/IGF2R; CD222 antigen
Gene ID : 3482
mRNA Refseq : NM_000876
Protein Refseq : NP_000867
MIM : 147280
UniProt ID : P11717
Chromosome Location : 6q25-q27
Pathway : Clathrin derivedvesicle budding; Golgi Associated Vesicle Biogenesis; Lysosome; MembraneTrafficking; trans-Golgi Network Vesicle Budding
Function : glycoproteinbinding; insulin-like growth factor binding; insulin-like growth factor-activatedreceptor activity; mannose binding; phosphoprotein binding; protein binding; receptoractivity; transporter activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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