"IGF2R" Related Products


Recombinant Human Insulin-Like Growth Factor 2 Receptor

Cat. No.: IGF2R-619H
Product Overview: Recombinant Human IGF2R is expressed in E.coli.
Description: IGF2R is a protein that inhumans is encoded by the IGF2R gene. IGF2R is a multifunctional proteinreceptor that binds insulin-like growth factor 2 (IGF2) at the cell surfaceand mannose-6-phosphate (M6P)-tagged proteins in the trans-Golgi network.
Source: Produced recombinantlyin E. coli.
Species: Human
Molecular Weight: 7.496 kDa-confirmedby Mass Spectrometry
Purity: Greaterthan 95 % (by HPLC and N-terminal sequence analysis)
Endotoxin Level: Less than 0.1 EU/μg
Biological Activity: Type 2 IGF receptorbinding assay: ED50 < 100 ng/ml; IGF binding protein assay: ED50> 1000 ng/ml; Stimulation of protein synthesis in rat L6 myoblasts:ED50 < 100 ng/ml
Stateand appearance: Dried from 0.1 Macetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa).
N-terminal sequenceanalysis: 7 residues Greater than 95 % single sequence
Storage: At least 2 years at 2-4°C (lyophilized).
OfficialSymbol: IGF2R
Gene Name: IGF2Rinsulin-like growth factor 2 receptor [ Homo sapiens ]
Synonyms: IGF2R; insulin-likegrowth factor 2 receptor; MPR1; MPRI; CD222; CIMPR; M6P-R; cation-independentmannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptorOTTHUMP00000017536; CI Man-6-p Receptor; CI-MPR; M6PR; 300 kDa mannose6-phosphate receptor; MPR 300; insulin-like growth factor II receptor; IGF-IIreceptor; M6P/IGF2 receptor; M6P/IGF2R; CD222 antigen
Gene ID: 3482
mRNA Refseq: NM_000876
Protein Refseq: NP_000867
MIM: 147280
UniProt ID: P11717
Chromosome Location: 6q25-q27
Pathway: Clathrin derivedvesicle budding; Golgi Associated Vesicle Biogenesis; Lysosome; MembraneTrafficking; trans-Golgi Network Vesicle Budding
Function: glycoproteinbinding; insulin-like growth factor binding; insulin-like growth factor-activatedreceptor activity; mannose binding; phosphoprotein binding; protein binding; receptoractivity; transporter activity

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