Recombinant Mouse Interleukin 22

• Cat.No.: Il22-639M
• Product Overview: Recombinant mouse Il22contains 2 x 146 amino acid chains.

Specification

• Cat. No.: Il22-639M
• Description: Mouse Interleukin22, also known as T cell-derived inducible factor (ILTIF), is a cytokine thatis structurally related to IL10. Studies have shown that Il22 induces acute-phase reactants in vitro and in vivo,suggesting that the cytokine contributes to the regulation of inflammatoryresponses.
• Source: E. coli
• Species: Mouse
• Form: Lyophilized from 10mM sodium citrate, pH 4.0.
• Molecular Weight: 33.4 kDa
• Purity: > 98% asdetermined by SDS-PAGE and HPLC analyses
• Endotoxin Level: < 0.1 ng/µg ofIL22
• Biological Activity: Recombinant mouseIL22 is fully biologically active when compared to a standard. The activityis determined by its ability to activiate STAT following receptor-ligandinteraction.
• Reconstitution: Centrifuge vialprior to opening. First add sterile distilled water to the vial to fully solubilizethe protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions.
• Storage: Store lyophilizedprotein at -20°C to -80°C. Reconstituted protein is stable for 1 week at 2-4°C.For long term storage, aliquot and store at -20°C with a carrier protein(0.1% HAS or BSA) as a stabilizer. Please note that the addition of anycarrier protein into this product may produce unwanted endotoxin. Thisdepends upon the particular application employed. Avoid repeated freeze-thawcycles.
• OfficialSymbol: Il22

Gene Information

• Gene Name: Il22 interleukin 22 [ Musmusculus ]
• Synonyms: Il22; interleukin22; IL-22; Iltif; IL-22a; ILTIFa; MGC129416; MGC129417; interleukin-22; ILTIFalpha; IL-TIF alpha; interleukin-22a; IL-10-related T-cell-derived-induciblefactor; interleukin 10-related T cell-derived inducible factor
• Gene ID: 50929
• mRNA Refseq: NM_016971
• Protein Refseq: NP_058667
• UniProt ID: Q9JJY9
• Chromosome Location: 10 D2; 10 67.0 cM
• Pathway: Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway
• Function: cytokine activity;protein binding