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Recombinant Human Pirin (iron-binding nuclear protein), His-tagged

Cat.No. : PIR-5547H
Product Overview : Recombinant humanPIR protein,fused to His-tag at N-terminus, was expressed in E. coli and purified byusing conventional chromatography.
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Cat. No. : PIR-5547H
Description : PIR, also known aspirin, is a memberof the cupin superfamily. PIR is an Fe(II)-containing nuclear proteinexpressed in all tissues of the body and concentrated within dot-likesubnuclear structures. Interactions with nuclear factor I/CCAAT boxtranscription factor as well as B cell lymphoma 3-encoded oncoprotein suggestthe encoded protein may act as a transcriptional cofactor and be involved inthe regulation of DNA transcription and replication.
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT.
Molecular Weight : 34.3 kDa (310aa)confirmed by MALDI-TOF
Purity : > 95%by SDS-PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSSKKVTLS VLSREQSEGV GARVRRSIGR PELKNLDPFL LFDEFKGGRPGGFPDHPHRG FETVSYLLEG GSMAHEDFCG HTGKMNPGDL QWMTAGRGIL HAEMPCSEEP AHGLQLWVNLRSSEKMVEPQ YQELKSEEIP KPSKDGVTVA VISGEALGIK SKVYTRTPTL YLDFKLDPGA KHSQPIPKGWTSFIYTISGD VYIGPDDAQQ KIEPHHTAVL GEGDSVQVEN KDPKRSHFVL IAGEPLREPV IQHGPFVMNTNEEISQAILD FRNAKNGFER AKTWKSKIGN
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoidrepeated freezing and thawing cycles.
Gene Name : PIR pirin (iron-binding nuclearprotein) [ Homo sapiens ]
Official Symbol : PIR
Synonyms : PIR;pirin (iron-binding nuclear protein); pirin; probablequercetinase; probable quercetin 2,3-dioxygenase PIR
Gene ID : 8544
mRNA Refseq : NM_001018109
Protein Refseq : NP_001018119
MIM : 603329
UniProt ID : O00625
Chromosome Location : Xp22.2
Function : metal ion binding;oxidoreductase activity; protein binding; quercetin 2,3-dioxygenase activity;transcription cofactor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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