| Cat. No.: | PPP3R2-973H |
| Product Overview: | Recombinant human PPP3R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description: | PPP3R2 is a calcium-dependent, calmodulin stimulated serine/threonine protein phosphatase. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Recombinant human PPP3R2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Formulation: | Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT. |
| Molecular Weight: | 22 kDa (193aa), confirmed by MALDI-TOF |
| Purity: | > 95% by SDS – PAGE |
| Concentration: | 0.5 mg/ml (determined by Bradford assay) |
| Sequences of animo acids: | MGSSHHHHHH SSGLVPRGSHMSTMGNEASY PAEMCSHFDN DEIKRLGRRF KKLDLDKSGS LSVEEFMSLP ELRHNPLVRR VIDVFDTDGD GEVDFKEFIL GTSQFSVKGD EEQKLRFAFSIYDMDKDGYI SNGELFQVLK MMVGNNLTDW QLQQLVDKTI IILDKDGDGK ISFEEFSAVV RDLEIHKKLV LIV |
| Storage: | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles. |
| Gene Name: | PPP3R2 protein phosphatase 3, regulatory subunit B, beta [ Homo sapiens ] |
| Synonyms: | PPP3R2;PPP3RL; protein phosphatase 3, regulatory subunit B, beta; Calcineurin subunit B type 2;Calcineurin B-like protein; Calcineurin BII; Protein phosphatase 2B regulatory subunit 2; Protein phosphatase 3 regulatory subunit B beta isoform; CBLP; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II);protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform |
| Gene ID: | 5535 |
| mRNA Refseq: | NM_147180 |
| Protein Refseq: | NP_671709 |
| UniProt ID: | Q96LZ3 |
| Chromosome Location: | 9q31 |
| Function: | calcium ion binding |
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