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Recombinant Human GATM protein, His-tagged

Cat.No. : GATM-1925H
Product Overview : Recombinant GATM protein was fused to His-tag and expressed in E.coli.
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Description : GATM (Glycine amidinotransferase, mitochondrial) is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. It plays a role in embryonic and central nervous system development. Recombinant human GATM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
Molecular Mass : 46.9 kDa
Protein length : 410
AA Sequence : MGSSHHHHHHSSGLVPRGSHMGSMS TQAATASSRNSCAADDKATEPLPKD CPVSSYNEWDPLEEVIVGRAENACV PPFTIEVKANTYEKYWPFYQKQGGH YFPKDHLKKAVAEIEEMCNILKTEG VTVRRPDPIDWSLKYKTPDFESTGL YSAMPRDILIVVGNEIIEAPMAWRS RFFEYRAYRSIIKDYFHRGAKWTTA PKPTMADELYNQDYPIHSVEDRHKL AAQGKFVTTEFEPCFDAADFIRAGR DIFAQRSQVTNYLGIEWMRRHLAPD YRVHIISFKDPNPMHIDATFNIIGP GIVLSNPDRPCHQIDLFKKAGWTII TPPTPIIPDDHPLWMSSKWLSMNVL MLDEKRVMVDANEVPIQKMFEKLGI TTIKVNIRNANSLGGGFHCWTCDVR RRGTLQSYLD
Purity : >90% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at +2 centigrade to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Bradford assay)
Gene Name : GATM
Official Symbol : GATM
Synonyms : AT; AGAT; CCDS3
Gene ID : 2628
mRNA Refseq : NM_001482.3
Protein Refseq : NP_001473.1
MIM : 602360
UniProt ID : P50440

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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