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Recombinant Mouse Lectin, Galactose Binding, Soluble 3

Cat. No.: Lgals3-5677M
Product Overview: Recombinant Mouse Lgals3protein was expressed in E. coli. Ala2-Ile264.
Description: The Lgals3constitute a large family of carbohydrate-binding proteins with specificityfor N-acetyl-lactosamine-containing glycoproteins. At least 14 mammalianLgals3, which share structural similarities in their carbohydrate recognitiondomains (CRD), have been identified. The Lgals3 have been classified into theprototype Lgals3, which contain one CRD and exist either as a monomer or anoncovalent homodimer; The chimera Lgals3 containing one CRD linked to anonlectin domain; and the tandem-repeat Lgals3 consisting of two CRDs joinedby a linker peptide.
Source: E. coli-derived.
Form: Lyophilized from a0.2 μm filtered solution in PBS, EDTA and DTT with BSA as a carrier protein.
N-terminalSequence: Ala2
Molecular Weight: 27.3 kDa
Activity: Measuredby its ability to agglutinate human red blood cells. Hadari, Y.R. et al.(2000) J. Cell Sci. 113:2385. The ED50 for this effect istypically 5-20 μg/mL.
Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution: 250μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 3 months, 2 to 8°C under sterileconditions after reconstitution.
Gene Name: Lgals3 lectin, galactosebinding, soluble 3 [ Mus musculus ]
Official Symbol: Lgals3
Synonyms: Lgals3;lectin, galactose binding, soluble 3; GBP; L-34; gal3; Mac-2; galectin-3;gal-3; CBP 35; lectin L-29; 35 kDa lectin; mac-2 antigen; igE-bindingprotein; laminin-binding protein; galactose-specific lectin 3; L-34galactoside-binding lectin; carbohydrate-binding protein 35; Lectin,galactose binding, soluble 3, isoform CRA_a; Lectin, galactose binding,soluble 3, isoform CRA_d; Uncharacterized protein; mCG_6908
Gene ID: 16854
mRNA Refseq: NM_010705
Protein Refseq: NP_034835
UniProt ID: Q8C253
Chromosome Location: 14 C1; 14
Function: protein binding;sugar binding

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