Active Recombinant Human MAM Domain Containing Glycosylphosphatidylinositol Anchor 1, His-tagged
Cat.No. : | MDGA1-5686H |
Product Overview : | Recombinant Human MDGA1protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag. Gln19-Gly931. |
- Specification
- Gene Information
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Cat. No. : | MDGA1-5686H |
Description : | MDGA1 is a 140 kDamember of the Ig superfamily of proteins. Human MDGA1 is synthesized as a 955amino acid (aa) precursor that contains an 18 aa signal sequence, a 914 aamature chain, and a 23 aa propeptide. The mature chain consists of sixIg-like domains, a fibronectin type III domain (aa 640-739), a MAM domain (aa751-918), 11 potential sites for N-linked glycosylation, and a GPI anchor (aa932). Alternative splicing in human MDGA1 produces an isoform variant thatshows a 48 aa substitution for aa corresponding to positions 926-955. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminalSequence : | Gln19 predicted |
Molecular Weight : | 101.9kDa |
Activity : | Measuredby its ability to enhance neurite outgrowth of E18 rat embryonic corticalneurons. Able to significantly enhance neurite outgrowth when immobilized at7.5-30 μg/Ml on a nitrocellulose-coated microplate. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
SDS-PAGE : | 120-140kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 500μg/mL in sterile PBS |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution. |
Gene Name : | MDGA1 MAM domain containingglycosylphosphatidylinositol anchor 1 [ Homo sapiens ] |
Official Symbol : | MDGA1 |
Synonyms : | MDGA1; MAM domaincontaining glycosylphosphatidylinositol anchor 1; GPIM; MAMDC3; FLJ45018;DKFZp686K0262; DKFZp686L0262; MAM domain-containingglycosylphosphatidylinositol anchor protein 1; GPI and MAM protein; MAMdomain-containing protein 3; glycosylphosphatidylinositol-MAM;glycosyl-phosphatidyl-inositol-MAM; OTTHUMP00000016331; OTTHUMP00000016332 |
Gene ID : | 266727 |
mRNA Refseq : | NM_153487 |
Protein Refseq : | NP_705691 |
MIM : | 609626 |
UniProt ID : | Q8NFP4 |
Chromosome Location : | 6p21 |
Function : | molecular function |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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