"Cxcl11" Related Products

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Recombinant Mouse Chemokine (C-X-C motif) Ligand 11

Cat. No. : Cxcl11-386M
Product Overview : Recombinantmouse Cxcl11 protein was expressed in E. coli. Phe22-Met100.
Description : Cxcl11 is a memberwithin the non-ELR CXC chemokine subgroup and has been designated Cxcl11.Cxcl11, together with MIG and IP10, constitute a subset of chemokines thatare ligands for CXCR3, a chemokine receptor that is primarily expressed onactivated Th1 cells and NK cells. The three chemokines were also reported to actas antagonists for CCR3, a chemokine receptor that is preferentiallyexpressed on activated Th2 cells.
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminal Sequence : Phe22
Molecular Weight : 9.1 kDa
Activity : Measured by itsability to chemoattract human CXCR3 transfected BaF3 mouse pro-B cells. TheED50 for this effect is typically 3-15 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
PDB rendering based on 1rjt. :

Gene Name : Cxcl11chemokine (C-X-C motif) ligand 11 [ Mus musculus ]
Official Symbol : Cxcl11
Synonyms : Cxcl11; chemokine(C-X-C motif) ligand 11; Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11;Scyb9b; betaR1; C-X-C motif chemokine 11; small-inducible cytokine B11;interferon-inducible T-cell alpha chemoattractant; small-inducible cytokinesubfamily B (Cys-X-Cys), member 11; I-TAC
Gene ID : 56066
mRNA Refseq : NM_019494
Protein Refseq : NP_062367
UniProt ID : Q9JHH5
Chromosome Location : 5
Pathway : Chemokine signalingpathway; Cytokine-cytokine receptor interaction; Toll-like receptor signalingpathway
Function : chemokine activity;cytokine activity

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