Recombinant Mouse Chemokine (C-X-C motif) Ligand 14 Cxcl14-388M

Recombinant Mouse Chemokine (C-X-C motif) Ligand 14


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Recombinant Mouse Chemokine (C-X-C motif) Ligand 14

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Cat. No. : Cxcl14-388M
Product Overview : Recombinantmouse Cxcl14 protein was expressed in E. coli. Ser23-Glu99.
Description : Cxcl14, also namedMIP2 gamma, KEC (kidney expressed chemokine), and BMAC (B cell andmonocyteactivating chemokine), is a member of the CXC chemokine superfamily. Thededuced 99 amino acid (aa) residue precursor has a 22 aa putative signalpeptide that is cleaved to produce the 77 aa mature protein. Mature human andmouse Cxcl14 differ by only 2 residues. Mouse Cxcl14 shares approximately 30%aa sequence identity with mouse MIP2. Unlike MIP2, Cxcl14 lacks the ELRdomain preceding the CXC motif.
Source : E. coli
Form : Supplied as a 0.2 μmfiltered solution in PBS.
N-terminal Sequence : Ser23
Molecular Weight : 9.4 kDa
Activity : Measured by itsability to induce calcium flux of prostaglandin E2 treated THP1 human acutemonocytic leukemia cells. 0.5 μg/mL of rmCxcl14 can significantly inducecalcium flux.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
Gene Name : Cxcl14chemokine (C-X-C motif) ligand 14 [ Mus musculus ]
Official Symbol : Cxcl14
Synonyms : Cxcl14; chemokine (C-X-C motif) ligand 14;KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; Scyb14; AI414372; bolekine; MIP2gamma;1110031L23Rik; 1200006I23Rik; C-X-C motif chemokine 14; chemokine BRAK;small-inducible cytokine B14; kidney-expressed chemokine CXC; musculus CXCchemokine MIP-2gamma; B-cell and monocyte-activating chemokine; smallinducible cytokine subfamily B (Cys-X-Cys), member 14; Bmac; Mip2g
Gene ID : 57266
mRNA Refseq : NM_019568
Protein Refseq : NP_062514
UniProt ID : Q9WUQ5
Chromosome Location : 13
Pathway : Chemokine signalingpathway; Cytokine-cytokine receptor interaction; Senescence and Autophagy
Function : chemokine activity;cytokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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