"NUDT10" Related Products

Recombinant Human NUDT10, His-tagged

Cat. No.: NUDT10-982H
Product Overview: Recombinant human NUDT10 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography(1-164aa).
Description: NUDT10, also known as APS2 or DIPP3α, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. It functions as a manganese-dependent polyphosphate phosphohydrolase with an optimum pH of 8.5. This protein specifically metabolizes diadendosine-polyphosphates and, to a lesser extent, diphosphoinositol polyphosphates.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Molecular Weight: 19.5 kDa (172aa) confirmed by MALDI-TOF
Purity: > 95% by SDS - PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids: MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPKHRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDPLEHHHH HH
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 [ Homo sapiens ]
Synonyms: NUDT10; APS2; DIPP3a; hDIPP3alpha; diphosphoinositol polyphosphate phosphohydrolase 3-alpha; hAps2; DIPP3-alpha; DIPP-3-alpha; nudix motif 10; OTTHUMP00000023298; nucleoside diphosphate-linked moiety X motif 10; diadenosine 5",5""-P1,P6-hexaphosphate hydrolase 3-alpha; diphosphoinositol polyphosphate phosphohydrolase type 3 alpha; NP_694853.1; EC 3.6.1.52
Gene ID: 170685
mRNA Refseq: NM_153183
Protein Refseq: NP_694853
MIM: 300527
UniProt ID: Q8NFP7
Chromosome Location: Xp11.23
Function: diphosphoinositol-polyphosphate diphosphatase activity; hydrolase activity; metal ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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