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Recombinant Human F11 Receptor, His-tagged

Cat.No. : F11R-6785H
Product Overview : Recombinant humanF11R protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques
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  • Gene Information
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Cat. No. : F11R-6785H
Description : F11R, also known asCD321, belongs to the immunoglobulin superfamily. It seems to plays a role inepithelial tight junction formation. Tight junctions represent one mode ofcell-to-cell adhesion in epithelial or endothelial cell sheets, formingcontinuous seals around cells and serving as a physical barrier to preventsolutes and water from passing freely through the paracellular space. F11Rprotein can act as (1) a receptor for reovirus, (2) a ligand for the integrinLFA1, involved in leukocyte transmigration, and (3) a platelet receptor
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl,1mM DTT
Molecular Weight : 25.8kDa (238aa),confirmed by MALDI-TOF
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby BCA assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMLGSVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV EWKFDQGDTT RLVCYNNKITASYEDRVTFLPTGITFKSVT REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAVLTCSEQDGSP PSEYTWFKDG IVMPTNPKSTRAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGTPMTSNAVRME AVERNVGV
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Cell adhesion molecules (CAMs);Epithelial cell signaling in Helicobacter pylori infection; Leukocytetransendothelial migration; Tight junction; Cell-cell adhesion systems;Hemostasis; Integrin cell surface interactions; Signaling in Immune system
Gene Name : F11RF11 receptor [ Homo sapiens ]
Official Symbol : F11R
Synonyms : F11R; F11 receptor; JAM; KAT; JAM1;JAMA; JCAM; CD321; PAM-1; junctional adhesion molecule 1; Junctional adhesionmolecule A; JAM-A; Junctional adhesion molecule 1; Platelet adhesion molecule1; JAM-1; OTTHUMP00000027880; Platelet F11 receptor; OTTHUMP00000027881;CD321 antigen
Gene ID : 50848
mRNA Refseq : NM_016946
Protein Refseq : NP_058642
MIM : 605721
UniProt ID : Q9Y624
Chromosome Location : 1q21.2-q21.3
Function : Protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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