Recombinant Human General Transcription Factor IIE, Polypeptide 2, Beta 34kDa, His-tagged
Cat.No. : | GTF2E2-466H |
Product Overview : | Recombinant humanGTF2E2 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography |
- Specification
- Gene Information
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Cat. No. : | GTF2E2-466H |
Description : | GTF2E2, also knownas TFIIE, is essential for transcription initiation by RNA polymerase II inconjunction with other general factors. TFIIE is a heterotetramer containingtwo subunits of relative molecular mass 57,000 (TFIIE-alpha) and two of34,000 (TFIIE-beta). TFIIE-beta is required in conjunction with TFIIE-alphafor transcription initiation. GTF2E2 recruits TFIIH to the initiation complexand stimulates the RNA polymerase II C-terminal domain kinase andDNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are requiredfor promoter clearance by RNA polymerase |
Form : | Liquid. 20mMTris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT |
Molecular Weight : | 35.6 kDa (315aa),confirmed by MALDI-TOF |
Purity : | > 90% by SDS -PAGE |
Concentration : | 1 mg/ml (determinedby Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMDPSLL RERELFKKRA LSTPVVEKRS ASSESSSSSS KKKKTKVEHG GSSGSKQNSDHSNGSFNLKA LSGSSGYKFG VLAKIVNYMK TRHQRGDTHP LTLDEILDET QHLDIGLKQK QWLMTEALVNNPKIEVIDGK YAFKPKYNVR DKKALLRLLD QHDQRGLGGI LLEDIEEALP NSQKAVKALG DQILFVNRPDKKKILFFNDK SCQFSVDEEF QKLWRSVTVD SMDEEKIEEY LKRQGISSMQ ESGPKKVAPI QRRKKPASQKKRRFKTHNEH LAGVLKDYSD ITSSK |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | GTF2E2 general transcriptionfactor IIE, polypeptide 2, beta 34kDa [Homo sapiens] |
Official symbol : | GTF2E2 |
Synonyms : | generaltranscription factor IIE, polypeptide 2, beta 34kDa; General transcriptionfactor IIE subunit 2; TF2E2; TFIIE-beta; FE; general transcription factorIIE, polypeptide 2 (beta subunit, 34kD); TFIIE-B; transcription initiationfactor IIE subunit beta; OTTHUMP00000225416 |
Gene ID : | 2961 |
mRNA Refseq : | NM_002095 |
Protein Refseq : | NP_002086 |
MIM : | 189964 |
Uniprot ID : | P29084 |
Chromosome Location : | 8p12 |
Pathway : | Basaltranscription factors, organism-specific biosystem; Basal transcriptionfactors, conserved biosystem; Eukaryotic Transcription Initiation,organism-specific biosystem; Formation and Maturation of mRNA Transcript,organism-specific biosystem; Gene Expression, organism-specific biosystem;HIV Infection, organism-specific biosystem |
Function : | DNA binding; protein binding |
Products Types
◆ Recombinant Protein | ||
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GTF2E2-1182H | Active Recombinant Human GTF2E2 | +Inquiry |
GTF2E2-2103C | Recombinant Chicken GTF2E2 | +Inquiry |
GTF2E2-30319TH | Recombinant Human GTF2E2, His-tagged | +Inquiry |
◆ Lysates | ||
GTF2E2-5701HCL | Recombinant Human GTF2E2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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