"CLC" Related Products

Recombinant Human Charcot-Leyden Crystal Protein, His-tagged

Cat. No.: CLC-984H
Product Overview: Recombinant human CLC protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques(1-142aa).
Description: Eosinophil lysophospholipase (CLC), also known as Galectin 10, act on biological membranes to regulate the multifunctional lysophospholipids. CLC is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 0.1M NaCl
Molecular Weight: 18.6 kDa (162aa) confirmed by MALDI-TOF
Purity: > 90% by SDS - PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay )
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSLLPVPYTE AASLSTGSTV TIKGRPLACF LNEPYLQVDF HTEMKEESDI VFHFQVCFGR RVVMNSREYGAWKQQVESKN MPFQDGQEFE LSISVLPDKY QVMVNGQSSY TFDHRIKPEA VKMVQVWRDI SLTKFNVSYL KR
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name: CLC Charcot-Leyden crystal protein [ Homo sapiens ]
Synonyms: CLC; GAL10; Gal-10; LGALS10; LGALS10A; MGC149659; LPPL_HUMAN; galectin-10; eosinophil lysophospholipase; galectin 10; lysolecithinacylhydrolase; NP_001819.2; EC 3.1.1.5
Gene ID: 1178
mRNA Refseq: NM_001828
Protein Refseq: NP_001819
MIM: 153310
UniProt ID: Q05315
Chromosome Location: 19q13.1
Function: hydrolase activity; lysophospholipase activity; lysophospholipase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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