"PPP1CC" Related Products

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Recombinant Human Protein Phosphatase 1, Catalytic Subunit, Gamma Isozyme, His-tagged

Cat. No.: PPP1CC-2401H
Product Overview: Recombinant humanPPP1CC protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography
Description: PPP1CC, also knownas serine/threonine-protein phosphatase PP1-gamma catalytic subunit, isessential for cell division, and participates in the regulation of glycogenmetabolism, muscle contractility and protein synthesis. This protein isinvolved in regulation of ionic conductances and long-term synapticplasticity and may play an important role in dephosphorylating substratessuch as the postsynaptic density-associated Ca2+/calmodulin dependent proteinkinase II
Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 50% glycerol, 0.2M NaCl, 2mM DTT
Molecular Weight: 39.1 kDa (343aa),confirmed by MALDI-TOF
Purity: > 85% by SDS -PAGE
Concentration: 0.25 mg/ml(determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLKICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASINRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGLLCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAPNYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKK
Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: PPP1CC protein phosphatase 1,catalytic subunit, gamma isozyme [ Homo sapiens ]
Official symbol: PPP1CC
Synonyms: PPP1CC; protein phosphatase 1,catalytic subunit, gamma isozyme; PPP1G; PP1gamma; erine/threonine-proteinphosphatase PP1-gamma catalytic subunitPP-1G; serine/threonine phosphatase1 gamma; protein phosphatase 1C catalytic subunit; protein phosphatase 1,catalytic subunit, gamma isoform; EC 3.1.3.16
Gene ID: 5501
mRNA Refseq: NM_002710
Protein Refseq: NP_002701
MIM: 176914
UniProt ID: P36873
Chromosome Location: 12q24.1-q24.2
Pathway: Focal adhesion; Insulin signalingpathway; Long-term potentiation; Oocyte meiosis; Regulation of actin cytoskeleton;Vascular smooth muscle contraction
Function: hydrolase activity; metal ionbinding; protein binding; protein kinase binding; protein serine/threoninephosphatase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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