Recombinant Human Regulator of G-protein Signaling 1, His-tagged
Cat.No. : | RGS1-6795H |
Product Overview : | Recombinant humanRGS1 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RGS1-6795H |
Description : | RGS1 is a member ofthe regulator of G-protein signalling family. This protein is located on thecytosolic side of the plasma membrane and contains a conserved, 120 aminoacid motif called the RGS domain. The protein attenuates the signallingactivity of G-proteins by binding to activated, GTP-bound G alpha subunitsand acting as a GTPase activating protein (GAP), increasing the rate ofconversion of the GTP to GDP. This hydrolysis allows the G alpha subunits tobind G beta/gamma subunit heterodimers, forming inactive G-proteinheterotrimers, thereby terminating the signal |
Form : | Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Weight : | 26 kDa (233aa),confirmed by MALDI-TOF |
Purity : | > 90% by SDS -PAGE |
Concentration : | 0.25 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMRAAAI STPKLDKMPG MFFSANPKEL KGTTHSLLDD KMQKRRPKTF GMDMKAYLRSMIPHLESGMK SSKSKDVLSA AEVMQWSQSL EKLLANQTGQ NVFGSFLKSE FSEENIEFWL ACEDYKKTESDLLPCKAEEI YKAFVHSDAA KQINIDFRTR ESTAKKIKAP TPTCFDEAQK VIYTLMEKDS YPRFLKSDIYLNLLNDLQAN SLK |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles |
Gene Name : | RGS1regulator of G-protein signaling 1 [ Homo sapiens ] |
Official Symbol : | RGS1 |
Synonyms : | RGS1; regulator of G-proteinsignaling 1; IER1, regulator of G protein signalling 1; 1R20; BL34; IR20;1R20; B cell activation protein BL34; B-cell activation protein BL34; BL34;Early response protein 1R20; IER 1; IER1; Immediate early response 1B cellspecific; IR20; Regulator of G protein signalling 1; Regulator of G-proteinsignaling 1; RGS 1; RGS1; RGS1_HUMAN; early response protein 1R20; B-cellactivation protein BL34; regulator of G-protein signalling 1; immediate-earlyresponse 1, B-cell specific; IER1 |
Gene ID : | 5996 |
mRNA Refseq : | NM_002922 |
Protein Refseq : | NP_002913 |
MIM : | 600323 |
Uniprot ID : | Q08116 |
Chromosome Location : | 1q31 |
Pathway : | CXCR4-mediated signaling events,organism-specific biosystem; Calcium Regulation in the Cardiac Cell,organism-specific biosystem; G alpha (i) signalling events, organism-specificbiosystem; GPCR downstream signaling, organism-specific biosystem; MyometrialRelaxation and Contraction Pathways, organism-specific biosystem |
Function : | GTPase activator activity;calmodulin binding; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
RGS1-4672R | Recombinant Rat RGS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS1-7563M | Recombinant Mouse RGS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS1-3689R | Recombinant Rhesus Macaque RGS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS1-8185H | Recombinant Human RGS1 protein, His & GST-tagged | +Inquiry |
RGS1-30015TH | Recombinant Human RGS1, His-tagged | +Inquiry |
◆ Lysates | ||
RGS1-1499HCL | Recombinant Human RGS1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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