Recombinant Human Mortality Factor 4 Like 1, His-tagged

• Cat.No.: MORF4L1-5582H
• Product Overview: Recombinant humanMORF4L1 protein, fused to His-tag at N-terminus, wasexpressed in E. coli and purified byusing conventional chromatography.

Specification

• Cat. No.: MORF4L1-5582H
• Description: MORF4L1, also knownas MRG15, belongs to the MRG family. This proteinis a componentof the NuA4 histone acetyltransferase (HAT) complex which is involved intranscriptional activation of select genes principally by acetylation of nucleosomalhistones H4 and H2A. MORF4L1 is a transcription factor expressed in avariety of human tissues, and its orthologs have been found in many othereukaryotes which constitute the MRG protein family. The C-terminal part ofMRG15 forms a conserved MRG domain which is involved in interactions with thetumor suppressor protein retinoblastoma and a nucleoprotein.
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT.
• Molecular Weight: 39.8 kDa (347aa)confirmed by MALDI-TOF
• Purity: > 85% by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMAPKQD PKPKFQEGER VLCFHGPLLY EAKCVKVAIK DKQVKYFIHYSGWNKNWDEW VPESRVLKYV DTNLQKQREL QKANQEQYAE GKMRGAAPGK KTSGLQQKNV EVKTKKNKQKTPGNGDGGST SETPQPPRKK RARVDPTVEN EETFMNRVEV KVKIPEELKP WLVDDWDLIT RQKQLFYLPAKKNVDSILED YANYKKSRGN TDNKEYAVNE VVAGIKEYFN VMLGTQLLYK FERPQYAEIL ADHPDAPMSQVYGAPHLLRL FVRIGAMLAY TPLDEKSLAL LLNYLHDFLK YLAKNSATLF SASDYEVAPP EYHRKAV
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: MORF4L1
• Function: protein binding; chromatin binding;protein N-terminus binding

Gene Information

• Gene Name: MORF4L1mortality factor 4 like 1 [ Homo sapiens ]
• Synonyms: MORF4L1; mortalityfactor 4 like 1; Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15; OTTHUMP00000248100;OTTHUMP00000248101; OTTHUMP00000248102; OTTHUMP00000185040; OTTHUMP00000185041;OTTHUMP00000185042; OTTHUMP00000185043; OTTHUMP00000185044; OTTHUMP00000185045;OTTHUMP00000185046; OTTHUMP00000185051; OTTHUMP00000185052; OTTHUMP00000185057;mortality factor 4-like protein 1; protein MSL3-1; MORF-related gene 15protein; Esa1p-associated factor 3 homolog; MORF-related gene on chromosome15; transcription factor-like protein MRG15; MGC10631
• Gene ID: 10933
• mRNA Refseq: NM_006791
• Protein Refseq: NP_006782
• MIM: 607303
• UniProt ID: Q9UBU8
• Chromosome Location: 15q24