"METAP1" Related Products

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Recombinant Human Methionyl Aminopeptidase 1, His-tagged

Cat. No.: METAP1-1960H
Product Overview: Recombinant humanMETAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.
Description: METAP1(Methionine aminopeptidase 1) belongs to the peptidase M24A family. Thisprotein removes the amino-terminal methionine from nascent proteins. Itrequired for normal progression through the cell cycle. The active site ofMetAP-1 contains two adjacent divalent metal ions connected by a watermolecule or hydroxide ion.
Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 3mM DTT, 40% glycerol, 200mM NaCl, 0.1mMPMSF.
Molecular Weight: 45.7kDa(409aa), confirmed by MALDI-TOF.
Purity: > 90%by SDS-PAGE
Concentration: 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSMAAVETR VCETDGCSSE AKLQCPTCIK LGIQGSYFCS QECFKGSWATHKLLHKKAKD EKAKREVSSW TVEGDINTDP WAGYRYTGKL RPHYPLMPTR PVPSYIQRPD YADHPLGMSESEQALKGTSQ IKLLSSEDIE GMRLVCRLAR EVLDVAAGMI KPGVTTEEID HAVHLACIAR NCYPSPLNYYNFPKSCCTSV NEVICHGIPD RRPLQEGDIV NVDITLYRNG YHGDLNETFF VGEVDDGARK LVQTTYECLMQAIDAVKPGV RYRELGNIIQ KHAQANGFSV VRSYCGHGIH KLFHTAPNVP HYAKNKAVGV MKSGHVFTIEPMICEGGWQD ETWPDGWTAV TRDGKRSAQF EHTLLVTDTG CEILTRRLDS ARPHFMSQF
Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: METAP1 methionyl aminopeptidase1 [ Homo sapiens ]
Official Symbol: METAP1
Synonyms: METAP1; methionyl aminopeptidase 1; MAP1A;MetAP1A; methionine aminopeptidase 1; MAP 1; metAP 1; peptidase M 1; EC3.4.11.18; KIAA0094; DKFZp781C0419; OTTHUMP00000219920
Gene ID: 23173
mRNA Refseq: NM_015143
Protein Refseq: NP_055958
MIM: 610151
UniProt ID: P53582
Chromosome Location: 4q23
Function: aminopeptidase activity; metal ion binding;metalloexopeptidase activity; peptidase activity

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