"ALDH18A1" Related Products

Recombinant Human Aldehyde Dehydrogenase 18 Family, Member A1, His-tagged

Cat. No.: ALDH18A1-486H
Product Overview: Recombinant Human ALDH18A1protein was expressed as 6 his-tagged fusion protein by E. coli and purifiedby Ni-sepharose. The purified protein was resolved in 1M PBS (58mM Na2HPO4, 17mMNaH2PO4, 68mM NaCl, pH8.) added with 300mM Imidazole and 0.7% Sarcosyl,15%glycerol. MW= 46 kDa.
Description: ALDH18A1 is a memberof the aldehyde dehydrogenase family and encodes a bifunctional ATP- andNADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase andgamma-glutamyl phosphate reductase activities. Alternatively splicedtranscript variants, encoding different isoforms, have been described for ALDH18A1.
Host: E. coli
Antigen peptideregion: 1-362aa
Molecular Weight: 46 kDa
Full length: False
Storage: Theprotein is stored in PBS buffer at -20°C. Repeatedfreeze-thaw cycles should be avoided.
Gene Name: ALDH18A1 aldehyde dehydrogenase18 family, member A1 [ Homo sapiens ]
Official Symbol: ALDH18A1
Synonyms: ALDH18A1;aldehyde dehydrogenase 18 family, member A1; P5CS; GSAS; PYCS; ARCL3A; MGC117316;delta-1-pyrroline-5-carboxylate synthase; delta1-pyrroline-5-carboxlatesynthetase; aldehyde dehydrogenase family 18 member A1; delta-1-pyrroline-5-carboxylatesynthetase; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehydesynthetase); EC 1.2.1.41; EC 2.7.2.11; OTTHUMP00000020159; OTTHUMP00000020160
Gene ID: 5832
mRNA Refseq: NM_002860
Protein Refseq: NP_002851
MIM: 138250
UniProt ID: P54886
Chromosome Location: 10q24.3
Pathway: Amino acid synthesisand interconversion (transamination); Arginine and proline metabolism;Metabolic pathways; Metabolism; Metabolism of amino acids and derivatives;Proline biosynthesis; Urea cycle and metabolism of amino groups; citrullinebiosynthesis; proline biosynthesis I
Function: ATP binding;glutamate 5-kinase activity; glutamate-5-semialdehyde dehydrogenase activity;kinase activity; nucleotide binding; oxidoreductase activity; transferaseactivity

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