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Recombinant Human HTR2A, His-tagged

Cat.No. : HTR2A-1729H
Product Overview : Recombinant Human HTR2A produced in E.Colicontains 6*his tag withthe plasmid PET28a.
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Cat. No. : HTR2A-1729H
Description : This gene encodesone of the receptors for serotonin, a neurotransmitterwith many roles.Mutations in this gene are associated with susceptibility toschizophrenia and obsessive-compulsive disorder, and arealso associated with response to the antidepressant citalopram in patientswith major depressive disorder (MDD). MDDpatients who also have a mutation in intron 2 of this gene show asignificantly reduced response to citalopram as this antidepressant downregulatesexpression of this gene. Multiple transcript variants encodingdifferent isoforms have been found for this gene.
Antigenpeptide region : 1-151aa
Source : E. coli.
StorageBuffer : 1MPBS (58mM Na2HPO4, 17mM NaH2PO4,68mM NaCl, pH8.) added with 300mM Imidazole and 0.7% Sarcosyl, 15% glycerol.
OfficialSymbol : HTR2A
Gene Name : HTR2A 5-hydroxytryptamine(serotonin) receptor 2A, G protein-coupled [ Homo sapiens ]
Synonyms : 5-hydroxytryptamine(serotonin)receptor 2A; HTR2; 5-HT2A; 5-HT2 receptor; Serotonin receptor 2A; 5-hydroxytryptaminereceptor 2A; 5-HT-2; OTTHUMP00000018378; 5-HT-2A; serotonin 5-HT-2A receptor;HTR2A; G protein-coupled
Gene ID : 3356
mRNA Refseq : NM_000621
Protein Refseq : NP_000612
MIM : 182135
UniProt ID : P28223
Chromosome Location : 13q14-q21
Pathway : GPCR ligand binding; Calcium signaling pathway; Gap junction
Function : drug binding; receptor activity; serotonin binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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