"BMP4" Related Products

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Recombinant Mouse BMP-4

Cat.No.: BMP4-583M
Product Overview: BMP-4 Mouse Recombinant produced in E.coli is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Description: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva
Source: E.coli
Species: Mouse
Bio-activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-15 ng/ml.
AA Sequence: KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCRKKNK NCRRHSLYVD FSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYL DEYDKVVLKN YQEMVVEGCG CR
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Gene Name: Bmp4 bone morphogenetic protein 4 [ Mus musculus ]
Official Symbol: Bmp4
Synonyms: BMP4; bone morphogenetic protein 4; BMP-2B; bone morphogenetic protein 2B; Bmp-4; Bmp2b; Bmp2b1; Bmp2b-1;
Gene ID: 12159
mRNA Refseq: NM_007554
Protein Refseq: NP_031580
Pathway: Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem
Function: BMP receptor binding; chemoattractant activity; cytokine activity; growth factor activity; heparin binding; protein binding; protein homodimerization activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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