Recombinant Human OTUB2, His-tagged

• Cat.No.: OTUB2-64H
• Product Overview: Recombinant human OTUB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques(1-234aa).

Specification

• Cat. No.: OTUB2-64H
• Description: OTUB2 (Ubiquitin thioesterase OTUB2) belongs to the peptidase C65 family. OTUB2 functions as a hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 50mM NaCl
• Molecular Weight: 29.4kDa (254aa) confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSETSFNLIS EKCDILSILR DHPENRIYRR KIEELSKRFTAIRKTKGDGN CFYRALGYSY LESLLGKSRE IFKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK VFNDQSASDH IVQFLRLLTS AFIRNRADFF RHFIDEEMDI KDFCTHEVEP MATECDHIQI TALSQALSIA LQVEYVDEMD TALNHHVFPE AATPSVYLLYKTSHYNILYA ADKH
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: OTUB2 OTU domain, ubiquitin aldehyde binding 2 [ Homo sapiens ]
• Synonyms: OTUB2; OTB2; OTU2; MGC3102; FLJ21916; C14orf137; ubiquitin thioesterase OTUB2; otubain-2; deubiquitinating enzyme OTUB2; ubiquitin-specific protease otubain 2; ubiquitin-specific-processing protease OTUB2; OTU domain-containing ubiquitin aldehyde-binding protein 2; NP_075601.1; EC 3.4.19.12
• Gene ID: 78990
• mRNA Refseq: NM_023112
• Protein Refseq: NP_075601
• MIM: 608338
• UniProt ID: Q96DC9
• Chromosome Location: 14q32.12
• Function: cysteine-type peptidase activity; omega peptidase activity; peptidase activity; protein binding; ubiquitin-specific protease activity