Recombinant Human ELAVL1(1-326aa), GST-tagged
Cat.No. : | ELAVL1-01H |
Product Overview : | Recombinant Human ELAVL1 full-length ORF (1 a.a. - 326 a.a.) fused with GST-tag at N-terminal, was expressed in vitro Wheat germ. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ELAVL1-01H |
Description : | ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. |
Source : | Wheat Germ |
Species : | Human |
Predicted MolecularMass : | 62.5 kDa |
AminoAcid Sequence : | MSNGYEDHMAEDCRGDIGRTNLIVN YLPQNMTQDELRSLFSSIGEVESAK LIRDKVAGHSLGYGFVNYVTAKDAE RAIN TLNGLRLQSKTIKVSYARPSSEVIK DANLYISGLPRTMTQKDVEDMFSRF GRIINSRVLVDQTTGLSRGVAFIRF DKRSEA EEAITSFNGHKPPGSSEPITVKFAA NPNQNKNVALLSQLYHSPARRFGGP VHHQAQRFRFSPMGVDHMSGLSGVN VPG NASSGWCIFIYNLGQDADEGILWQM FGPFGAVTNVKVIRDFNTNKCKGFG FVTMTNYEEAAMAIASLNGYRLGDK ILQVS FKTNKSHK |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer. |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot |
Stability& Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
OfficialSymbol : | ELAVL1 |
Gene Name : | ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [ Homo sapiens ] |
Synonyms : | ELAVL1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1 |
Gene ID : | 1994 |
mRNA Refseq : | NM_001419 |
Protein Refseq : | NP_001410 |
MIM : | 603466 |
UniProt ID : | Q15717 |
Chromosome Location : | 19p13.2 |
Pathway : | Gene Expression; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements; Stabilization of mRNA by HuR |
Function : | AU-rich element binding; RNA binding; mRNA binding; nucleotide binding; protein binding; tein kinase binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudies have shown that the ELAVL1 gene may be involved in the regulation of the immune system, especially in the inflammatory response.
The protein encoded by the ELAVL1 gene is mainly located in the cytoplasm and nucleus.
In some tumors, the expression level of ELAVL1 gene may be increased or decreased, which is related to the occurrence and progression of tumors.
This gene may play an important role in the process of apoptosis, but its specific mechanism of action still needs further research.
ELAVL1 is involved in the differentiation of nerve cells by binding to and stabilizing neuronal cell-specific microRNAs.
This gene isexpressed in many tissues and organs, including the brain, heart, liver, muscles, etc.
Customer Reviews (3)
Write a reviewIt is very pure and can be used with confidence.
In enzymatic experiments, ELAVL1 was found to have high catalytic efficiency.
In immunological experiments, it was found that ELAVL1 had good antigenicity and could induce target immune response.
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