Recombinant Mouse Agt protein, His-tagged
Cat.No. : | Agt-6860M |
Product Overview : | Recombinant Mouse Agt protein(P11859)(Met1-Val477), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Molecular Mass : | The secreted recombinant mouse AGT consists of 464 amino acids and has a calculated molecular mass of 50.8 kDa. The apparent molecular mass of the recombinant mouse AGT is approximately 58 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Protein Length : | Met1-Val477 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 96 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) [ Mus musculus ] |
Official Symbol : | Agt |
Synonyms : | AGT; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); angiotensinogen; serpin A8; angiotensin I; angiotensin ll; AngI; AngII; Aogen; AI265500; Serpina8; |
Gene ID : | 11606 |
mRNA Refseq : | NM_007428 |
Protein Refseq : | NP_031454 |
Products Types
◆ Recombinant Protein | ||
AGT-221R | Recombinant Rat AGT Protein, His (Fc)-Avi-tagged | +Inquiry |
Agt-01M | Recombinant Mouse Agt Protein | +Inquiry |
AGT-572H | Recombinant Human AGT Protein, His-tagged | +Inquiry |
AGT-95H | Recombinant Human AGT Protein, His-tagged | +Inquiry |
Agt-96M | Recombinant Mouse Agt Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
AGT-152H | Native Human Angiotensinogen | +Inquiry |
◆ Lysates | ||
AGT-2575HCL | Recombinant Human AGT cell lysate | +Inquiry |
AGT-1842MCL | Recombinant Mouse AGT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAGT is produced and released by the kidneys, and it plays a role in regulating renal blood flow and glomerular filtration rate, thereby impacting overall kidney function.
AGT is the precursor molecule for angiotensin peptides, including angiotensin I and angiotensin II, which are key regulators of blood pressure, fluid balance, and cardiovascular homeostasis.
AGT-derived angiotensin II plays a critical role in vasoconstriction, sodium reabsorption, and the regulation of aldosterone secretion, all of which influence blood pressure.
AGT and the renin-angiotensin system have been implicated in the central regulation of blood pressure, fluid balance, and neuroendocrine functions.
AGT is cleaved by the enzyme renin to generate angiotensin I, which is subsequently converted to angiotensin II by the enzyme angiotensin-converting enzyme (ACE).
AGT expression is regulated by various factors, including hormones (such as aldosterone and glucocorticoids), cytokines, and environmental stimuli.
AGT and its derivatives, such as angiotensin II, can promote inflammation and tissue remodeling through interactions with receptors and signaling pathways.
Experimental techniques used to study AGT include molecular biology approaches, gene expression analysis, protein quantification, immunohistochemistry, and animal models.
Genetic variations in the AGT gene have been associated with an increased risk of hypertension, cardiovascular diseases, and other conditions influenced by the renin-angiotensin system.
AGT levels and the renin-angiotensin system play a role in regulating blood pressure during pregnancy, and dysregulation can contribute to disorders such as preeclampsia.
Customer Reviews (5)
Write a reviewThe proteins offering reliable results and contributing to the success of my experiments.
The customer service team was incredibly helpful and responsive to my inquiries.
The product allowed me to access high-quality reagents while staying within my budget.
The ordering process was seamless, and the company's efficient shipping ensured that I received the recombinant proteins promptly and in excellent condition.
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