Active Recombinant Human RETN
Cat.No. : | RETN-61H |
- Specification
- Gene Information
- Related Products
Cat. No. : | RETN-61H |
Overview : | Human Resistin Recombinant Protein was expressed in E. coli with amino acids Ser17-Pro108 accession number NP_065148. |
Description : | Resistin is a peptide hormone belonging to the RELM (Resistin-Like Molecule) family that also includes RELMα, RELMβ, and RELMγ. In mice, resistin is secreted in high levels by adipocytes, and overexpression has been linked to insulin resistance and obesity. The link between resistin and glucose metabolism in humans is still unclear, and it has instead been found to play a role in the inflammatory process. The main source of resistin in humans is peripheral blood monocytes, which upregulate expression in response to IL-6 and TNFα. Elevated levels of circulating resistin are associated with chronic inflammatory conditions and cardiovascular disease. |
Source : | E. coli |
Species : | Human |
Predicted MolecularMass : | 9.9 kDa |
Formulation : | Sterile liquid; phosphate buffered saline 1% BSA, pH 7.2. 0.22 um filtered. |
Purity : | > 97%, as determined by SDS-PAGE |
Concentration : | 0.1 mg/mL |
Endotoxin : | Less than 0.1 ng/ug cytokine as determined by the LAL assay. |
Bioactivity : | The ED50 of this protein, as measured by stimulation of lypolysis in human adipocytes, is 7-30 ug/mL. This corresponds to a specific activity of 143-33 Units/mg. |
Handling Conditions : | For best recovery, quick-spin vial prior to opening. Use in sterile envrioment. |
Storage : | Store at less than or equal to -70°C. |
OfficialSymbol : | RETN |
Gene Name : | RETN resistin [ Homo sapiens ] |
Synonyms : | RETN; Cysteine-rich secreted protein; FIZZ3; Adipose tissue-specific secretory factor (ADSF); C/EBP-epsilon; regulated myeloid-sepcific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like-2; ADSF; MGC126603; MGC126609; RETN1; XCP1; resistin; MGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1 ; Adipose tissue-specific secretory factor; C/EBP-epsilon regulated myeloid-specific secreted; cysteine-rich protein precursor 1; cysteine-rich protein; Cysteine-rich secreted protein FIZZ3; found in inflammatory zone 3 |
Gene ID : | 56729 |
mRNA Refseq : | NM_020415 |
Protein Refseq : | NP_065148 |
MIM : | 605565 |
UniProt ID : | Q9HD89 |
Chromosome Location : | 19p13.2 |
Pathway : | Adipogenesis, organism-specific biosystem |
Function : | hormone activity |
Products Types
◆ Recombinant Protein | ||
Retn-5467M | Recombinant Mouse Retn Protein, Myc/DDK-tagged | +Inquiry |
RETN-774B | Recombinant Bovine RETN Protein (19-109 aa), His-tagged | +Inquiry |
RETN-3670R | Recombinant Rhesus Macaque RETN Protein, His (Fc)-Avi-tagged | +Inquiry |
RETN-012H | Recombinant Human RETN Protein, His-tagged | +Inquiry |
RETN-1882H | Recombinant Human RETN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
RETN-1635MCL | Recombinant Mouse RETN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionExpression level of RETN is associated with the development of insulin resistance. High levels of RETN can reduce insulin sensitivity, leading to decreased glycemic control, which promotes the development of insulin resistance.
Studies have shown that regulating the expression level of RETN can influence the development and treatment effect of diabetes and cardiovascular disease. For example, certain drugs can improve insulin sensitivity and control blood sugar levels by inhibiting the expression level of RETN.
Diabetes and cardiovascular disease can be predicted and diagnosed by measuring the expression level of RETN. For example, high levels of RETN may indicate a higher risk of disease and more severe disease conditions.
Mutations and expression levels of the RETN gene can be detected to aid in diagnosing disease and assessing prognosis. For example, certain mutations may predict a higher risk and a worse prognosis.
Mutations or abnormal expression of RETN may be associated with a variety of diseases. For example, certain mutations can lead to abnormally elevated levels of their expression, increasing the risk of diabetes, cardiovascular disease, etc.
RETN has some association with other biomarkers. For example, in obesity and cardiovascular disease, the expression level of RETN can be used to assess the prognosis and therapeutic effect of the disease together with biomarkers such as adiponectin and leptin.
Customer Reviews (3)
Write a reviewCatalytic activity of RETN is excellent, no matter what the environment can maintain stable catalytic performance, its reliability is reliable.
The quality of RETN they produce is guaranteed, and we can buy it with confidence.
The stability of RETN is too strong to ignore, and it remains admirably stable after long storage.
Ask a Question for All RETN Products
Required fields are marked with *
My Review for All RETN Products
Required fields are marked with *
Inquiry Basket