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Recombinant Human Midkine (neurite growth-promoting factor 2), His-tagged

Cat.No. : MDK-6917H
Product Overview : Recombinant human MDK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 15.7 kDa.
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Description : MDK is a basic heparin-binding growth factor of low molecular weight, a member of the NEGF family whose founding member is pleiotrophin. This protein exhibits neurite outgrowth-promoting activity and may play a role in nervous system development and/or maintenance. MDK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl 2mM DTT, and 20% Glycerol.
Molecular Mass : 15.7 kDa (144aa), confirmed by MALDI-TOF.
Protein length : 21-143aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MVAKKKDKVK KGGPGSECAE WAWGPCTPSS KDCGVGFREG TCGAQTQRIR CRVPCNWKKE FGADCKYKFE NWGACDGGTG TKVRQGTLKK ARYNAQCQET IRVTKPCTPK TKAKAKAKKG KGKD
Endotoxin : < 1.0 eu per 1 μg of protein (determined by lal
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : MDK midkine (neurite growth-promoting factor 2) [ Homo sapiens ]
Official Symbol : MDK
Synonyms : MDK; midkine (neurite growth-promoting factor 2); NEGF2; midkine; FLJ27379; MK; ARAP; amphiregulin-associated protein; midgestation and kidney protein; neurite outgrowth-promoting protein; neurite outgrowth-promoting factor 2;
Gene ID : 4192
mRNA Refseq : NM_001012333
Protein Refseq : NP_001012333
MIM : 162096
UniProt ID : P21741
Chromosome Location : 11p11.2
Pathway : Glypican 2 network, organism-specific biosystem; Syndecan-4-mediated signaling events, organism-specific biosystem;
Function : growth factor activity; growth factor activity; heparin binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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