Recombinant Human Tropomyosin 4, His-tagged
Cat.No. : | TPM4-6899H |
Product Overview : | Recombinant human TPM4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 30.7 kDa. |
- Specification
- Gene Information
- Related Products
Description : | TPM4 belongs to the tropomyosin family. Tropomyosins are present in virtually all eukaryotic cells (both muscle and nonmuscle), where they bind actin filaments and function to modulate actin-myosin interaction and stabilize actin filament structure. TPM4 binds to actin filaments in muscle and nonmuscle cells and plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl. |
Molecular Mass : | 30.7 kDa (268aa), confirmed by MALDI-TOF |
Protein length : | 1-248aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI |
Purity : | >85% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | TPM4 tropomyosin 4 [ Homo sapiens ] |
Official Symbol : | TPM4 |
Synonyms : | TPM4; tropomyosin 4; tropomyosin alpha-4 chain; TM30p1; tropomyosin-4; |
Gene ID : | 7171 |
mRNA Refseq : | NM_001145160 |
Protein Refseq : | NP_001138632 |
MIM : | 600317 |
UniProt ID : | P67936 |
Chromosome Location : | 19p13.1 |
Pathway : | Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem; |
Function : | actin binding; calcium ion binding; structural constituent of muscle; |
Products Types
◆ Recombinant Protein | ||
TPM4-9539M | Recombinant Mouse TPM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM4-2424H | Recombinant Human TPM4 Protein, MYC/DDK-tagged | +Inquiry |
Tpm4-6601M | Recombinant Mouse Tpm4 Protein, Myc/DDK-tagged | +Inquiry |
TPM4-5901R | Recombinant Rat TPM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM4-3371H | Recombinant Human TPM4, GST-tagged | +Inquiry |
◆ Lysates | ||
TPM4-1036HCL | Recombinant Human TPM4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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