"KRT14" Related Products

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Recombinant Human Keratin 14, His-tagged

Cat.No.: KRT14-467H
Product Overview: Recombinant human KRT14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 53.8 kDa.
Description: KRT14 is a member of the cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. It functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3 sigma to mediate protein synthesis.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea.
Molecular Mass: 53.8 kDa (492aa)
Protein length: 1-472aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MTTCSRQFTS SSSMKGSCGI GGGIGGGSSR ISSVLAGGSC RAPSTYGGGL SVSSSRFSSG GAYGLGGGYG GGFSSSSSSF GSGFGGGYGG GLGTGLGGGF GGGFAGGDGL LVGSEKVTMQ NLNDRLASYL DKVRALEEAN ADLEVKIRDW YQRQRPAEIK DYSPYFKTIE DLRNKILTAT VDNANVLLQI DNARLAADDF RTKYETELNL RMSVEADING LRRVLDELTL ARADLEMQIE SLKEELAYLK KNHEEEMNAL RGQVGGDVNV EMDAAPGVDL SRILNEMRDQ YEKMAEKNRK DAEEWFFTKT EELNREVATN SELVQSGKSE ISELRRTMQN LEIELQSQLS MKASLENSLE ETKGRYCMQL AQIQEMIGSV EEQLAQLRCE MEQQNQEYKI LLDVKTRLEQ EIATYRRLLE GEDAHLSSSQ FSSGSQSSRD VTSSSRQIRT KVMDVHDGKV VSTHEQVLRT KN
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1.0 mg/ml (determined by Bradford assay)
Gene Name: KRT14 keratin 14 [ Homo sapiens ]
Official Symbol: KRT14
Synonyms: KRT14; keratin 14; EBS3, EBS4, keratin 14 (epidermolysis bullosa simplex, Dowling Meara, Koebner); keratin, type I cytoskeletal 14; epidermolysis bullosa simplex; Dowling Meara; Koebner; CK-14; keratin-14; cytokeratin 14; cytokeratin-14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); K14; NFJ; CK14; EBS3; EBS4;
Gene ID: 3861
mRNA Refseq: NM_000526
Protein Refseq: NP_000517
MIM: 148066
UniProt ID: P02533
Chromosome Location: 17q12-q21
Pathway: Glucocorticoid receptor regulatory network, organism-specific biosystem;
Function: protein binding; structural constituent of cytoskeleton;

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