"TNFSF18" Related Products

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Recombinant Human Tumor Necrosis Factor (ligand) Superfamily, Member 18

Cat.No.: TNFSF18-6887H
Product Overview: Recombinant human TNFSF18 protein was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 14.6 kDa.
Description: TNFSF18 belongs to the tumor necrosis factor(TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Source: E. coli
Species: Human
Tag: N/A
Form: Liquid. In 10mM sodium citrate (pH 3.5), 10% glycerol, 1mMDTT.
Molecular Mass: 14.6 kDa (129aa), confirmed by MALDI-TOF.
Protein length: 72-199aa
AA Sequence: MQLETAKEPC MAKFGPLPSK WQMASSEPPC VNKVSDWKLE ILQNGLYLIY GQVAPNANYN DVAPFEVRLY KNKDMIQTLT NKSKIQNVGG TYELHVGDTI DLIFNSEHQV LKNNTYWGII LLANPQFIS
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5mg/ml (determined by Bradford assay)
Gene Name: TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 [ Homo sapiens ]
Official Symbol: TNFSF18
Synonyms: TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18; AITRL; hGITRL; TL6; AITR ligand; GITR ligand; activation-inducible TNF-related ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; GITRL; MGC138237;
Gene ID: 8995
mRNA Refseq: NM_005092
Protein Refseq: NP_005083
MIM: 603898
UniProt ID: Q9UNG2
Chromosome Location: 1q23
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding;

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