Recombinant Human NmrA-Like Family Domain Containing 1, His-tagged

• Cat.No.: NMRAL1-6837H
• Product Overview: Recombinant human NMRAL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: NMRAL1 is a redox sensor protein that undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.15M NaCl.
• Molecular Mass: 35.9kDa(323aa) confirmed by MALDI-TOF
• Protein length: 1-299aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVDKKL VVVFGGTGAQ GGSVARTLLE DGTFKVRVVT RNPRKKAAKE LRLQGAEVVQ GDQDDQVIME LALNGAYATF IVTNYWESCS QEQEVKQGKL LADLARRLGL HYVVYSGLEN IKKLTAGRLA AAHFDGKGEV EEYFRDIGVP MTSVRLPCYF ENLLSHFLPQ KAPDGKSYLL SLPTGDVPMD GMSVSDLGPV VLSLLKMPEK YVGQNIGLST CRHTAEEYAA LLTKHTRKVV HDAKMTPEDY EKLGFPGARD LANMFRFYAL RPDRDIELTL RLNPKALTLD QWLEQHKGDF NLL
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: NMRAL1 NmrA-like family domain containing 1 [ Homo sapiens ]
• Official Symbol: NMRAL1
• Synonyms: NMRAL1; NmrA-like family domain containing 1; nmrA-like family domain-containing protein 1; FLJ25918; HSCARG; SDR48A1; short chain dehydrogenase/reductase family 48A; member 1; short chain dehydrogenase/reductase family 48A, member 1
• Gene ID: 57407
• mRNA Refseq: NM_020677
• Protein Refseq: NP_065728
• UniProt ID: Q9HBL8
• Chromosome Location: 16p13.3
• Function: nucleotide binding