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Recombinant Human HscB Iron-Sulfur Cluster Co-Chaperone Homolog (E. coli), His-tagged

Cat.No. : HSCB-6850H
Product Overview : Recombinant human HSCB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : HSCB belongs to the hscB family and contains 1 J domain. This protein is expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart and localized to mitochondria and cytoplasm. It may act as a co-chaperone in iron-sulfur cluster assembly in mitochondria, Interacts with ISCU and HSPA9.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl.
Molecular Mass : 26.7kDa(231aa) confirmed by MALDI-TOF
Protein length : 30-235aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMAASQA GSNYPRCWNC GGPWGPGRED RFFCPQCRAL QAPDPTRDYF SLMDCNRSFR VDTAKLQHRY QQLQRLVHPD FFSQRSQTEK DFSEKHSTLV NDAYKTLLAP LSRGLYLLKL HGIEIPERTD YEMDRQFLIE IMEINEKLAE AESEAAMKEI ESIVKAKQKE FTDNVSSAFE QDDFEEAKEI LTKMRYFSNI EEKIKLKKIP L
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : HSCB HscB iron-sulfur cluster co-chaperone homolog (E. coli) [ Homo sapiens ]
Official Symbol : HSCB
Synonyms : HSCB; HscB iron-sulfur cluster co-chaperone homolog (E. coli); JAC1; HSC20; DNAJC20; dJ366L4.2; iron-sulfur cluster co-chaperone protein HscB, mitochondrial; J-type co-chaperone HSC20; dnaJ homolog subfamily C member 20; DnaJ (Hsp40) homolog, subfamily C, member 20; Jac1
Gene ID : 150274
mRNA Refseq : NM_172002
Protein Refseq : NP_741999
MIM : 608142
UniProt ID : Q8IWL3
Chromosome Location : 22q12.1
Pathway : Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem
Function : chaperone binding; heat shock protein binding; metal ion binding; molecular_function; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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