Recombinant Mouse Chemokine (C-C motif) Ligand 3, His-tagged

• Cat.No.: Ccl3-7197M
• Product Overview: Recombinant mouse CCL3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10.4 kDa.

Specification

• Description: C-C motif chemokine 3, also known as CCL3, belongs to the intercrine beta (chemokine CC) family. CCL3 has a potent chemotactic activity for eosinophils. This protein is binding to a high-affinity receptor activates calcium release in neutrophils.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Liquid. In 20mM Sodium citrate buffer (pH 3.5) containing 10% glycerol.
• Molecular Mass: 10.4 kDa (93aa) confirmed by MALDI-TOF
• Protein length: 24-92aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAPYGAD TPTACCFSYS RKIPRQFIVD YFETSSLCSQ PGVIFLTKRN RQICADSKET WVQEYITDLE LNA
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Ccl3 chemokine (C-C motif) ligand 3 [ Mus musculus ]
• Official Symbol: Ccl3
• Synonyms: CCL3; chemokine (C-C motif) ligand 3; C-C motif chemokine 3; TY-5; L2G25B; MIP1 (a); SIS-alpha; MIP-1 alpha; MIP-1-alpha; small inducible cytokine A3; small-inducible cytokine A3; heparin-binding chemotaxis protein; macrophage inflammatory protein-1alpha; macrophage inflammatory protein 1-alpha; Mip1a; Scya3; G0S19-1; AI323804; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha
• Gene ID: 20302
• mRNA Refseq: NM_011337
• Protein Refseq: NP_035467
• Pathway: Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem
• Function: CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; calcium-dependent protein kinase C activity; chemoattractant activity; chemokine activity; chemokine activity; cytokine activity; kinase activity; phospholipase activator activity; protein binding; protein kinase activity