"NDUFAF1" Related Products

Recombinant Human NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor 1, His-tagged

Cat.No.: NDUFAF1-7207H
Product Overview: Recombinant human NDUFAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 37 kDa.
Description: NDUFAF1 is a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The protein is required for assembly of complex I, and mutations in this protein are a cause of mitochondrial complex I deficiency.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT, 2mM EDTA.
Molecular Mass: 37 kDa (326aa), confirmed by MALDI-TOF
Protein length: 25-327aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSYPFLGIR FAEYSSSLQK PVASPGKASS QRKTEGDLQG DHQKEVALDI TSSEEKPDVS FDKAIRDEAI YHFRLLKDEI VDHWRGPEGH PLHEVLLEQA KVVWQFRGKE DLDKWTVTSD KTIGGRSEVF LKMGKNNQSA LLYGTLSSEA PQDGESTRSG YCAMISRIPR GAFERKMSYD WSQFNTLYLR VRGDGRPWMV NIKEDTDFFQ RTNQMYSYFM FTRGGPYWQE VKIPFSKFFF SNRGRIRDVQ HELPLDKISS IGFTLADKVD GPFFLEIDFI GVFTDPAHTE EFAYENSPEL NPRLFK
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: NDUFAF1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 [ Homo sapiens ]
Official Symbol: NDUFAF1
Synonyms: NDUFAF1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1; complex I intermediate-associated protein 30, mitochondrial; CGI 65; CIA30; NADH-ubiquinone oxidoreductase 1 alpha subcomplex, assembly factor 1; CGI65; CGI-65;
Gene ID: 51103
mRNA Refseq: NM_016013
Protein Refseq: NP_057097
MIM: 606934
UniProt ID: Q9Y375
Chromosome Location: 15q11.2-q21.3
Function: protein binding; unfolded protein binding;

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