Active Recombinant Human interleukin 2
Cat.No. : | IL2-741H |
Product Overview : | Recombinant human IL2 was overexpressed in E. coli and purified by conventional chromatography. MW: 15.4 kDa. |
- Specification
- Gene Information
- Related Products
Description : | IL2 is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2 signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. |
Source : | E. coli |
Species : | Human |
Tag : | N/A |
Form : | Liquid. 20mM MES buffer (pH5.0). |
Bio-activity : | The ED50 for this effect is< 1.5 ng/ml. measured in a cell proliferation assay using ctll2 mouse cytotoxic t> |
Molecular Mass : | 15.4 kDa (133 aa), confirmed by MALDI-TOF. |
AA Sequence : | MPTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFSQSIIS TLT |
Endotoxin : | < 1.0 eu per 1 ug of protein (determined by lal |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by BCA assay) |
Gene Name : | IL2 interleukin 2 [ Homo sapiens ] |
Official Symbol : | IL2 |
Synonyms : | IL2; interleukin 2; interleukin-2; IL 2; T cell growth factor; TCGF; aldesleukin; involved in regulation of T-cell clonal expansion; IL-2; lymphokine; |
Gene ID : | 3558 |
mRNA Refseq : | NM_000586 |
Protein Refseq : | NP_000577 |
MIM : | 147680 |
UniProt ID : | P60568 |
Chromosome Location : | 4q26-q27 |
Pathway : | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; |
Function : | carbohydrate binding; cytokine activity; glycosphingolipid binding; growth factor activity; interleukin-2 receptor binding; interleukin-2 receptor binding; kappa-type opioid receptor binding; kinase activator activity; |
Products Types
◆ Recombinant Protein | ||
IL2-1027P | Recombinant Pig IL2 Protein, His-tagged | +Inquiry |
IL2-159R | Active Recombinant Rat IL2 Protein | +Inquiry |
IL2-1118H | Recombinant Human IL2 Protein (Ala21-Thr153), Biotinylated | +Inquiry |
IL2-157P | Active Recombinant Porcine IL2 Protein | +Inquiry |
IL2-158P | Active Recombinant Porcine IL2 Protein | +Inquiry |
◆ Lysates | ||
IL2-5234HCL | Recombinant Human IL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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